换一批Antroquinonol administration in animal preclinical studies for Alzheimer's disease (AD): A new avenue for modifying progression of AD pathophysiology.
第一作者：
Fernandez,Francesca
第一单位：
School of Behavioural and Health Sciences, Faculty of Health Sciences, Australian Catholic University, 1100 Nudgee Rd, Banyo, Queensland, 4014, Australia.;Centre for Genomics and Personalised Medicine, Genomics Research Centre, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia.
作者：
关键词
AD biomarkersAICD, APP Intracellular Cytoplasmic/C-terminal DomainAMPK, 5′ adenosine monophosphate-activated protein kinaseAPP, Amyloid precursor proteinAPPβ, secreted amino-terminals APPβ fragmentAlzheimer's disease (AD)Animal model of ADAntroquinonolAβ, amyloid-β peptidesBehavioural testingCTFα, carboxyterminal fragment-αCTFβ, carboxyterminal fragment-βGSK3β, Glycogen synthase kinase 3 betaIFNγ, Interferon gammaIL-1, Interleukin 1IL-6, Interleukin 6Inflammatory markersMAPK, Mitogen activated protein kinaseNF-kB, nuclear factor kappa-light-chain-enhancer of activated B cellsNMDA Rc, methyl-D-aspartate receptors receptorROS, reactive oxygen speciesTNF-α, Tumor Necrosis factor alphaTransgenic micecdck5, cyclin dependant kinase 5sAPPα, secreted amino-terminals APPα fragment
DOI
10.1016/j.bbih.2022.100435
PMID
35252893
发布时间
2022-03-08
- 浏览3
Brain, behavior, & immunity - health
2022年21卷
100435页
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