Cancer's second genome: Microbial cancer diagnostics and redefining clonal evolution as a multispecies process: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution.

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作者： Gregory D,Sepich-Poore ^[1] ; Caitlin,Guccione ^[2] ; Lucie,Laplane ^[3] ; Thomas,Pradeu ^[4] ; Kit,Curtius ^[5] ; Rob,Knight ^[6]

作者单位： Department of Bioengineering, University of California San Diego, La Jolla, California, 92093, USA. ^[1] Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, California, 92093, USA. ^[2] Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, California, 92093, USA. ^[3] Department of Pediatrics, University of California San Diego, La Jolla, California, 92093, USA. ^[4] Institut d'histoire et de philosophie des sciences et des techniques (UMR8590), CNRS & Panthéon-Sorbonne University, 75006 Paris, France. ^[5] Hematopoietic stem cells and the development of myeloid malignancies (UMR1287), Gustave Roussy Cancer Campus, 94800 Villejuif, France. ^[6] ImmunoConcept (UMR5164), CNRS & University of Bordeaux, 33076 Bordeaux Cedex, France. ^[7] Department of Computer Science and Engineering, University of California San Diego, La Jolla, California, 92093, USA. ^[8]

关键词 cancer microbiome clonal evolution diagnostics prognostics therapeutic modulation

主题词生物进化(Biological Evolution);人类(Humans);肿瘤(Neoplasms)

DOI 10.1002/bies.202100252

PMID 35253252

发布时间 2023-11-04

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