换一批
第一作者：
Lijun,Shao
第一单位：
The National Center for Drug Screening and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai 201203, China.;School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.;University of Chinese Academy of Sciences, Beijing 100049, China.
作者：
关键词
AMY, amylinAllosteric modulationBRET, bioluminescence resonance energy transferBmax, maximum measured BRET valueCGRP, calcitonin gene-related peptideCLR, calcitonin-like receptorEC50, half maximal effective concentrationECD, extracellular domainEmax, maximal responseG protein-coupled receptorGCGR, glucagon receptorGHRHR, hormone-releasing hormone receptorGIPR, gastric inhibitory polypeptide receptor or glucose-dependent insulinotropic polypeptideGLP-1R, glucagon-like peptide-1 receptorGLP-2R, glucagon-like peptide-2 receptorGPCRs, G protein-coupled receptorsGPCR–RAMP interactionGlucagon receptor familyLigand selectivityRAMP, receptor activity-modulating proteinReceptor activity-modulating proteinReceptor pharmacologyRluc, Renilla luciferaseSBA, suspension bead arraySCTR, secretin receptorSV, splice variantSignalingTMD, transmembrane domainVPAC2R, vasoactive intestinal polypeptide 2 receptorcAMP, cyclic adenosine monophosphatepEC50, negative logarithm of EC50β2-AR, β2-adrenergic receptor
DOI
10.1016/j.apsb.2021.07.028
PMID
35256936
发布时间
2022-03-09
- 浏览1
Acta pharmaceutica Sinica. B
2022年12卷2期
637-650页
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