Structural (dys)connectivity associates with cholinergic cell density in Alzheimer's disease.

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作者： Chen Pei,Lin ^[1] ; Irene,Frigerio ^[1] ; Baayla D C,Boon ^[2] ; Zihan,Zhou ^[3] ; Annemieke J M,Rozemuller ^[4] ; Femke H,Bouwman ^[2] ; Menno M,Schoonheim ^[3] ; Wilma D J,van de Berg ^[1] ; Laura E,Jonkman ^[1]

作者单位： Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Department of Anatomy and Neurosciences, Amsterdam Neuroscience, Amsterdam, The Netherlands. ^[1] Amsterdam UMC, location VUmc, Vrije Universiteit Amsterdam, Department of Pathology, Amsterdam Neuroscience, Amsterdam, The Netherlands. ^[2] Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Department of Neurology, Alzheimer centrum Amsterdam, Amsterdam, The Netherlands. ^[3] Zhejiang University, College of Biomedical Engineering and Instrument Science, Zhejiang, China. ^[4]

关键词 Alzheimer’s disease cholinergic neurons histopathology nucleus basalis of Meynert post-mortem diffusion MRI

主题词阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);萎缩(Atrophy);迈内特基底核(Basal Nucleus of Meynert);细胞计数(Cell Count);胆碱能药(Cholinergic Agents);人类(Humans)

DOI 10.1093/brain/awac093

PMID 35259207

发布时间 2022-09-12

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