Various Subtypes of EGFR Mutations in Patients With NSCLC Define Genetic, Immunologic Diversity and Possess Different Prognostic Biomarkers.

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第一作者： Youming,Lei

第一单位： Department of Geriatric Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.

作者： Youming,Lei ^[1] ; Kun,Wang ^[2] ; Yinqiang,Liu ^[1] ; Xuming,Wang ^[3] ; Xudong,Xiang ^[4] ; Xiangu,Ning ^[5] ; Wanbao,Ding ^[6] ; Jin,Duan ^[1] ; Dingbiao,Li ^[7] ; Wei,Zhao ^[1] ; Yi,Li ^[8] ; Fujun,Zhang ^[1] ; Xiaoyu,Luo ^[1] ; Yunfei,Shi ^[1] ; Ying,Wang ^[7] ; Depei,Huang ^[9] ; Yuezong,Bai ^[9] ; Hushan,Zhang ^[9]

作者单位： Department of Geriatric Thoracic Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China. ^[1] Department of Thoracic Surgery, Anning First Peoples Hospital affiliate to Kunming University of Science and Technology (Kunming Forth People's Hospital), Kunming, China. ^[2] Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China. ^[3] Department of Thoracic Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, China. ^[4] Department of Thoracic Surgery, The First Peoples Hospital of Yunnan Province, Kunming, China. ^[5] Department of Oncology, Yan'an Hospital Affiliated to Kunming Medical University, Kunming, China. ^[6] Department of Thoracic Surgery, Yan'an Hospital Affiliated to Kunming Medical University, Kunming, China. ^[7] Department of Oncology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, China. ^[8] The Medical Department, 3D Medicines Inc., Shanghai, China. ^[9]

关键词 EGFR - epidermal growth factor receptor NSCLC biomarkers immune microenviroment prognosis

主题词癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);人类(Humans);肺肿瘤(Lung Neoplasms);突变(Mutation);预后(Prognosis);肿瘤微环境(Tumor Microenvironment)

DOI 10.3389/fimmu.2022.811601

PMID 35265073

发布时间 2022-05-31

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