Evolution from a first clinical demyelinating event to multiple sclerosis in the REFLEX trial: Regional susceptibility in the conversion to multiple sclerosis at disease onset and its amenability to subcutaneous interferon beta-1a.

导出 OA

翻译打印收藏纠错

作者： Marco,Battaglini ^[1] ; Hugo,Vrenken ^[2] ; Riccardo,Tappa Brocci ^[1] ; Giordano,Gentile ^[1] ; Ludovico,Luchetti ^[1] ; Adriaan,Versteeg ^[2] ; Mark S,Freedman ^[3] ; Bernard M J,Uitdehaag ^[4] ; Ludwig,Kappos ^[5] ; Giancarlo,Comi ^[6] ; Andrea,Seitzinger ^[7] ; Dominic,Jack ^[8] ; Maria Pia,Sormani ^[9] ; Frederik,Barkhof ^[2] ; Nicola,De Stefano ^[10]

作者单位： Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy. ^[1] Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, The Netherlands. ^[2] Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada. ^[3] Department of Neurology, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands. ^[4] Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) and Neurology, Departments of Head, Spine and Neuromedicine, Biomedical Engineering and Clinical Research, University Hospital, University of Basel, Basel, Switzerland. ^[5] Casa di Cura Privata del Policlinico, Università Vita-Salute San Raffaele, Milan, Italy. ^[6] Global Biostatistics, Merck Healthcare KGaA, Darmstadt, Germany. ^[7] Global Medical Affairs, Merck Serono Ltd (an affiliate of Merck KGaA), Feltham, UK. ^[8] Department of Health Sciences, University of Genoa, Genoa, Italy. ^[9] UCL Institutes of Neurology and Healthcare Engineering, London, UK. ^[10]

关键词 first clinical demyelinating event interferon-beta lesions white matter tracts

主题词人类(Humans);磁共振成像(Magnetic Resonance Imaging);多发性硬化(Multiple Sclerosis);多发性硬化, 复发缓解性(Multiple Sclerosis, Relapsing-Remitting);反射(Reflex);治疗结果(Treatment Outcome)

DOI 10.1111/ene.15314

PMID 35274413

发布时间 2022-07-31

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交