Elevated expression of RAB3B plays important roles in chemoresistance and metastatic potential of hepatoma cells.

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作者： Ryouichi,Tsunedomi ^[1] ; Kiyoshi,Yoshimura ^[2] ; Yuta,Kimura ^[3] ; Mitsuo,Nishiyama ^[3] ; Nobuyuki,Fujiwara ^[3] ; Satoshi,Matsukuma ^[3] ; Shinsuke,Kanekiyo ^[3] ; Hiroto,Matsui ^[3] ; Yoshitaro,Shindo ^[3] ; Yusaku,Watanabe ^[3] ; Yukio,Tokumitsu ^[3] ; Shin,Yoshida ^[3] ; Michihisa,Iida ^[3] ; Nobuaki,Suzuki ^[3] ; Shigeru,Takeda ^[3] ; Tatsuya,Ioka ^[4] ; Shoichi,Hazama ^[5] ; Hiroaki,Nagano ^[3]

作者单位： Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. tsune-r@yamaguchi-u.ac.jp. ^[1] Department of Clinical Research in Tumor Immunology, Showa University Clinical Research Institute for Clinical Pharmacology and Therapeutics, Shinagawa, Tokyo, 142-8555, Japan. ^[2] Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. ^[3] Oncology Center, Yamaguchi University Hospital, Ube, Yamaguchi, 755-8505, Japan. ^[4] Department of Translational Research and Developmental Therapeutics against Cancer, Yamaguchi University Faculty of Medicine, Ube, Yamaguchi, 755-8505, Japan. ^[5]

关键词 Cancer stem cell Exosome Hepatoma RAB3B Sphere