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Neoadjuvant in situ vaccination with cowpea mosaic virus as a novel therapy against canine inflammatory mammary cancer.

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第一作者： Daniel,Alonso-Miguel

第一单位： Department of Animal Medicine, Surgery and Pathology, Mammary Oncology Unit, Veterinary Teaching Hospital, Veterinary Medicine School, Complutense University of Madrid, Madrid, Spain.

作者： Daniel,Alonso-Miguel ^[1] ; Guillermo,Valdivia ^[1] ; Diego,Guerrera ^[2] ; Maria Dolores,Perez-Alenza ^[1] ; Stanislav,Pantelyushin ^[2] ; Angela,Alonso-Diez ^[1] ; Veronique,Beiss ^[3] ; Steven,Fiering ^[4] ; Nicole F,Steinmetz ^[5] ; Maria,Suarez-Redondo ^[1] ; Johannes,Vom Berg ^[2] ; Laura,Peña ^[1] ; Hugo,Arias-Pulido ^[6]

作者单位： Department of Animal Medicine, Surgery and Pathology, Mammary Oncology Unit, Veterinary Teaching Hospital, Veterinary Medicine School, Complutense University of Madrid, Madrid, Spain. ^[1] Institute of Laboratory Animal Science, University of Zurich, Schlieren, Switzerland. ^[2] Department of Biomedical Engineering, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.;Department of NannoEngineering, University of California San Diego, La Jolla, California, USA. ^[3] Department of Microbiology and Immunology, and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth and Dartmouth Hitchcock Health, Dartmouth College Geisel School of Medicine, Lebanon, New Hampshire, USA. ^[4] Department of Biomedical Engineering, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.;Department of NannoEngineering, University of California San Diego, La Jolla, California, USA.;Department of Radiology, University of California San Diego, La Jolla, California, USA.;Department of Bioengineering, University of California San Diego, La Jolla, California, USA.;Moores Cancer Center, University of California San Diego, La Jolla, California, USA.;Center for Nano-ImmunoEngineering, University of California San Diego, La Jolla, California, USA.;Institute for Materials Discovery and Design, University of California San Diego, La Jolla, California, USA. ^[5] Department of Microbiology and Immunology, and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth and Dartmouth Hitchcock Health, Dartmouth College Geisel School of Medicine, Lebanon, New Hampshire, USA hugo.ariaspulido@dartmouth.edu. ^[6]

关键词 breast neoplasms drug evaluation, preclinical immunogenicity, vaccine neutrophil Infiltration vaccination