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Observation versus screening spinal MRI and pre-emptive treatment for spinal cord compression in patients with castration-resistant prostate cancer and spinal metastases in the UK (PROMPTS): an open-label, randomised, controlled, phase 3 trial.

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第一作者: David,Dearnaley
第一单位: Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK; Urology Unit, Royal Marsden NHS Foundation Trust, London, UK.
作者单位: Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK; Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. [1] Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK. [2] Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. [3] Clinical Oncology, The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust, King's Lynn, UK. [4] Clinical Oncology, The Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, UK. [5] Radiology, St George's University Hospitals NHS Foundation Trust, London, UK. [6] Imaging Science and Technology, University of Dundee, Dundee, UK. [7] Clinical Oncology, University of Leeds, Leeds, UK. [8] Clinical Oncology, Barking, Havering and Redbridge University Hospitals NHS Trust, London, UK. [9] Clinical Oncology, East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK. [10] Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK. [11] Clinical Oncology, Cardiff University, Cardiff, UK. [12] Clinical Oncology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK. [13] Clinical Oncology, University College London Hospitals NHS Foundation Trust, London, UK. [14] Clinical Oncology, University Hospitals Dorset NHS Foundation Trust, Poole, UK. [15] Clinical Oncology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK. [16] Clinical Oncology, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK. [17] Clinical Oncology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. [18] Clinical Oncology, Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK. [19] Clinical Oncology, Somerset NHS Foundation Trust, Taunton, UK. [20] Oncology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK. [21] Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK. Electronic address: emma.hall@icr.ac.uk. [22]
DOI 10.1016/S1470-2045(22)00092-4
PMID 35279270
发布时间 2025-05-30
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The Lancet. Oncology

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