首页> Journal of thrombosis and haemostasis : JTH> Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.

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第一作者： Gerard,Temprano-Sagrera

第一单位： Genomics of Complex Disease Unit, Sant Pau Biomedical Research Institute. IIB-Sant Pau, Barcelona, Spain.

作者： Gerard,Temprano-Sagrera ^[1] ; Colleen M,Sitlani ^[2] ; William P,Bone ^[3] ; Miguel,Martin-Bornez ^[1] ; Benjamin F,Voight ^[4] ; Alanna C,Morrison ^[5] ; Scott M,Damrauer ^[6] ; Paul S,de Vries ^[5] ; Nicholas L,Smith ^[7] ; Maria,Sabater-Lleal ^[8]

作者单位： Genomics of Complex Disease Unit, Sant Pau Biomedical Research Institute. IIB-Sant Pau, Barcelona, Spain. ^[1] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA. ^[2] Genomics and Computational Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. ^[3] Department of Systems Pharmacology and Translational Therapeutics and Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.;Institute of Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. ^[4] Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA. ^[5] Department of Surgery and Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.;Corporal Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA. ^[6] Department of Epidemiology, University of Washington, Seattle, Washington, USA.;Kaiser Permanente Washington Health Research Institute, Kaiser Permanente, Seattle, Washington, USA.;Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, Washington, USA. ^[7] Genomics of Complex Disease Unit, Sant Pau Biomedical Research Institute. IIB-Sant Pau, Barcelona, Spain.;Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden. ^[8]

关键词 blood coagulation cardiovascular diseases genetic pleiotropy genome-wide association study hemostasis