首页> Annals of oncology : official journal of the European Society for Medical Oncology> Residual ctDNA after treatment predicts early relapse in patients with early-stage non-small cell lung cancer.

Residual ctDNA after treatment predicts early relapse in patients with early-stage non-small cell lung cancer.

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第一作者： D,Gale

第一单位： Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK; Cancer Research UK Cambridge Centre - Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK.

作者： D,Gale ^[1] ; K,Heider ^[1] ; A,Ruiz-Valdepenas ^[1] ; S,Hackinger ^[2] ; M,Perry ^[2] ; G,Marsico ^[2] ; V,Rundell ^[3] ; J,Wulff ^[3] ; G,Sharma ^[2] ; H,Knock ^[3] ; J,Castedo ^[4] ; W,Cooper ^[1] ; H,Zhao ^[1] ; C G,Smith ^[1] ; S,Garg ^[5] ; S,Anand ^[5] ; K,Howarth ^[2] ; D,Gilligan ^[6] ; S V,Harden ^[7] ; D M,Rassl ^[4] ; R C,Rintoul ^[8] ; N,Rosenfeld ^[9]

作者单位： Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK; Cancer Research UK Cambridge Centre - Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK. ^[1] Inivata Ltd, The Glenn Berge Building, Babraham Research Park, Babraham, Cambridge, UK. ^[2] Cambridge Clinical Trials Unit - Cancer Theme, Cambridge, UK. ^[3] Cancer Research UK Cambridge Centre - Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK. ^[4] Cancer Molecular Diagnostics Laboratory, Clifford Allbutt Building, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. ^[5] Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK; Addenbrooke's Hospital, Cambridge, UK. ^[6] Addenbrooke's Hospital, Cambridge, UK. ^[7] Cancer Research UK Cambridge Centre - Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK; Department of Oncology, University of Cambridge Hutchison-MRC Research Centre, Cambridge Biomedical Campus, Cambridge, UK. Electronic address: rcr39@cam.ac.uk. ^[8] Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK; Cancer Research UK Cambridge Centre - Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK; Inivata Ltd, The Glenn Berge Building, Babraham Research Park, Babraham, Cambridge, UK. Electronic address: nitzan.rosenfeld@cruk.cam.ac.uk. ^[9]

关键词 cell-free DNA (cfDNA)circulating tumour DNA (ctDNA)early detection liquid biopsy minimal residual disease (MRD)non-small cell lung cancer (NSCLC)

医学主题词癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);疾病恶化(Disease Progression);人类(Humans);肺肿瘤(Lung Neoplasms);肿瘤复发, 局部(Neoplasm Recurrence, Local);前瞻性研究(Prospective Studies);小细胞肺癌(Small Cell Lung Carcinoma)

DOI 10.1016/j.annonc.2022.02.007

PMID 35306155

发布时间 2025-05-30

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