QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment.

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第一作者： Kaspar,Bresser

第一单位： Division of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

作者： Kaspar,Bresser ^[1] ; Meike E W,Logtenberg ^[2] ; Mireille,Toebes ^[1] ; Natalie,Proost ^[2] ; Justin,Sprengers ^[1] ; Bjorn,Siteur ^[3] ; Manon,Boeije ^[3] ; Lona J,Kroese ^[3] ; Ton N,Schumacher ^[3]

作者单位： Division of Molecular Oncology & Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands. ^[1] Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands. ^[2] Preclinical Intervention Unit, Mouse Clinic for Cancer and Ageing, The Netherlands Cancer Institute, Amsterdam, The Netherlands. ^[3] Transgenic Facility, Mouse Clinic for Cancer and Aging Research, the Netherlands Cancer Institute, Amsterdam, The Netherlands. ^[4]

关键词 QPCTL cancer-associated fibroblasts genetically modified mouse model tumor micro-environment

主题词动物(Animals);免疫疗法(Immunotherapy);巨噬细胞(Macrophages);黑色素瘤(Melanoma);小鼠(Mice);单核细胞(Monocytes);肿瘤微环境(Tumor Microenvironment)

DOI 10.1080/2162402X.2022.2049486

PMID 35309731

发布时间 2022-04-29

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