首页> Aging cell> Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function.

Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function.

导出 OA

翻译打印收藏纠错

第一作者： Marie-Laure,Arotcarena

第一单位： Univ. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.

作者： Marie-Laure,Arotcarena ^[1] ; Federico N,Soria ^[2] ; Anthony,Cunha ^[3] ; Evelyne,Doudnikoff ^[1] ; Geoffrey,Prévot ^[4] ; Jonathan,Daniel ^[5] ; Mireille,Blanchard-Desce ^[5] ; Philippe,Barthélémy ^[6] ; Erwan,Bezard ^[1] ; Sylvie,Crauste-Manciet ^[6] ; Benjamin,Dehay ^[1]

作者单位： Univ. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France. ^[1] Univ. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.;Achucarro Basque Center for Neuroscience, Dpto. Neurociencias, Universidad del País Vasco (UPV/EHU), Leioa, Spain. ^[2] Univ. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.;Université de Bordeaux, INSERM U1212, CNRS, UMR 5320, ARNA ARN: Régulations Naturelle et Artificielle, ChemBioPharm, Bordeaux, France. ^[3] Univ. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.;Université de Bordeaux, INSERM U1212, CNRS, UMR 5320, ARNA ARN: Régulations Naturelle et Artificielle, ChemBioPharm, Bordeaux, France.;Biomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. ^[4] Université de Bordeaux, Institut des Sciences Moléculaires, CNRS, UMR 5255, Talence, France. ^[5] Université de Bordeaux, INSERM U1212, CNRS, UMR 5320, ARNA ARN: Régulations Naturelle et Artificielle, ChemBioPharm, Bordeaux, France. ^[6]

关键词 Parkinson's disease acidic nanoparticles alpha-synuclein, neurodegeneration, therapeutics in vivo lysosomal restoration