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Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study.

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作者: Liewei,Wang [1] ; Steven E,Scherer [2] ; Suzette J,Bielinski [3] ; Donna M,Muzny [4] ; Leila A,Jones [5] ; John Logan,Black [6] ; Ann M,Moyer [6] ; Jyothsna,Giri [5] ; Richard R,Sharp [7] ; Eric T,Matey [8] ; Jessica A,Wright [8] ; Lance J,Oyen [8] ; Wayne T,Nicholson [9] ; Mathieu,Wiepert [10] ; Terri,Sullard [5] ; Timothy B,Curry [11] ; Carolyn R,Rohrer Vitek [5] ; Tammy M,McAllister [5] ; Jennifer L,St Sauver [12] ; Pedro J,Caraballo [13] ; Konstantinos N,Lazaridis [14] ; Eric,Venner [4] ; Xiang,Qin [15] ; Jianhong,Hu [4] ; Christie L,Kovar [4] ; Viktoriya,Korchina [4] ; Kimberly,Walker [4] ; HarshaVardhan,Doddapaneni [15] ; Tsung-Jung,Wu [4] ; Ritika,Raj [4] ; Shawn,Denson [4] ; Wen,Liu [4] ; Gauthami,Chandanavelli [4] ; Lan,Zhang [4] ; Qiaoyan,Wang [15] ; Divya,Kalra [15] ; Mary Beth,Karow [6] ; Kimberley J,Harris [6] ; Hugues,Sicotte [6] ; Sandra E,Peterson [6] ; Amy E,Barthel [6] ; Brenda E,Moore [6] ; Jennifer M,Skierka [6] ; Michelle L,Kluge [6] ; Katrina E,Kotzer [6] ; Karen,Kloke [6] ; Jessica M,Vander Pol [6] ; Heather,Marker [5] ; Joseph A,Sutton [10] ; Adrijana,Kekic [16] ; Ashley,Ebenhoh [8] ; Dennis M,Bierle [13] ; Michael J,Schuh [17] ; Christopher,Grilli [16] ; Sara,Erickson [18] ; Audrey,Umbreit [19] ; Leah,Ward [17] ; Sheena,Crosby [17] ; Eric A,Nelson [16] ; Sharon,Levey [20] ; Michelle,Elliott [21] ; Steve G,Peters [22] ; Naveen,Pereira [23] ; Mark,Frye [24] ; Fadi,Shamoun [25] ; Matthew P,Goetz [26] ; Iftikhar J,Kullo [23] ; Robert,Wermers [27] ; Jan A,Anderson [8] ; Christine M,Formea [8] ; Razan M,El Melik [8] ; John D,Zeuli [8] ; Joseph R,Herges [8] ; Carrie A,Krieger [8] ; Robert W,Hoel [8] ; Jodi L,Taraba [8] ; Scott R,St Thomas [5] ; Imad,Absah [28] ; Matthew E,Bernard [29] ; Stephanie R,Fink [30] ; Andrea,Gossard [31] ; Pamela L,Grubbs [32] ; Therese M,Jacobson [32] ; Paul,Takahashi [30] ; Sharon C,Zehe [33] ; Susan,Buckles [34] ; Michelle,Bumgardner [32] ; Colette,Gallagher [34] ; Kelliann,Fee-Schroeder [5] ; Nichole R,Nicholas [5] ; Melody L,Powers [35] ; Ahmed K,Ragab [5] ; Darcy M,Richardson [5] ; Anthony,Stai [10] ; Jaymi,Wilson [5] ; Joel E,Pacyna [7] ; Janet E,Olson [36] ; Erica J,Sutton [7] ; Annika T,Beck [7] ; Caroline,Horrow [7] ; Krishna R,Kalari [37] ; Nicholas B,Larson [37] ; Hongfang,Liu [38] ; Liwei,Wang [38] ; Guilherme S,Lopes [39] ; Bijan J,Borah [40] ; Robert R,Freimuth [38] ; Ye,Zhu [41] ; Debra J,Jacobson [37] ; Matthew A,Hathcock [37] ; Sebastian M,Armasu [37] ; Michaela E,McGree [37] ; Ruoxiang,Jiang [37] ; Tyler H,Koep [42] ; Jason L,Ross [42] ; Matthew G,Hilden [42] ; Kathleen,Bosse [42] ; Bronwyn,Ramey [42] ; Isabelle,Searcy [42] ; Eric,Boerwinkle [43] ; Richard A,Gibbs [44] ; Richard M,Weinshilboum [45]
作者单位: Center for Individualized Medicine, Mayo Clinic, Rochester, MN; Division of Clinical Pharmacology, Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN. [1] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX. [2] Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN. [3] Human Genome Sequencing Center Clinical Laboratory, Baylor College of Medicine, Houston, TX. [4] Center for Individualized Medicine, Mayo Clinic, Rochester, MN. [5] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN. [6] Biomedical Ethics Research Program, Mayo Clinic, Rochester, MN. [7] Department of Pharmacy, Mayo Clinic, Rochester, MN. [8] Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN. [9] Department of Information Technology, Mayo Clinic, Rochester, MN. [10] Center for Individualized Medicine, Mayo Clinic, Rochester, MN; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN. [11] Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN. [12] Division of General Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [13] Center for Individualized Medicine, Mayo Clinic, Rochester, MN; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [14] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX. [15] Department of Pharmacy, Mayo Clinic, Phoenix, AZ. [16] Department of Pharmacy, Mayo Clinic, Jacksonville, FL. [17] Supply Chain Management, Mayo Clinic, Rochester, MN. [18] Department of Pharmacy, Mayo Clinic Health System, Mankato, MN. [19] Department of Clinical Genomics, Mayo Clinic, Scottsdale, AZ. [20] Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [21] Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [22] Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. [23] Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN. [24] Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ. [25] Division of Medical Oncology, Department of Oncology, Mayo Clinic, Rochester, MN. [26] Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [27] Division of Pediatric Gastroenterology and Hepatology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN. [28] Department of Family Medicine, Mayo Clinic, Rochester, MN. [29] Division of Community Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [30] Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN. [31] Department of Nursing, Mayo Clinic, Rochester, MN. [32] Legal Department, Mayo Clinic, Rochester, MN. [33] Department of Public Affairs, Mayo Clinic, Rochester, MN. [34] Biospecimens Accessioning and Processing Laboratory, Mayo Clinic, Rochester, MN. [35] Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Biomedical Ethics Research Program, Mayo Clinic, Rochester, MN. [36] Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN. [37] Department of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN. [38] Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN. [39] Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN; Division of Health Care Policy and Research, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN. [40] Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN. [41] OneOme, LLC, Minneapolis, MN. [42] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX; Human Genome Sequencing Center Clinical Laboratory, Baylor College of Medicine, Houston, TX; School of Public Health, University of Texas Health Science Center at Houston (UTHealth), Houston, TX. [43] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX. Electronic address: agibbs@bcm.edu. [44] Center for Individualized Medicine, Mayo Clinic, Rochester, MN; Division of Clinical Pharmacology, Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN. Electronic address: weinshilboum.richard@mayo.edu. [45]
DOI 10.1016/j.gim.2022.01.022
PMID 35331649
发布时间 2024-06-07
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Genetics in medicine : official journal of the American College of Medical Genetics

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