Resveratrol Inhibited ADAM10 Mediated CXCL16-Cleavage and T-Cells Recruitment to Pancreatic β-Cells in Type 1 Diabetes Mellitus in Mice.

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作者： Mohamed S,Abdel-Bakky ^[1] ; Abdulmajeed,Alqasoumi ^[2] ; Waleed M,Altowayan ^[3] ; Elham,Amin ^[3] ; Mostafa A,Darwish ^[4]

作者单位： Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah 52471, Saudi Arabia. ^[1] Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt. ^[2] Department of Pharmacy Practice, College of Pharmacy, Qassim University, Buraydah 52471, Saudi Arabia. ^[3] Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni Suef 62514, Egypt. ^[4] Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraydah 52471, Saudi Arabia. ^[5] Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni Suef 11787, Egypt. ^[6]

关键词 ADAM10 CXCL16 NF-κβ T1D apoptosis pancreatic islets resveratrol

DOI 10.3390/pharmaceutics14030594

PMID 35335970

发布时间 2022-03-29

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