RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13.

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第一作者： Zhi-Dong,Zhang

第一单位： Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Department of Pulmonary and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.;Cancer Center, Renmin Hospital of Wuhan University, Wuhan, 430061, China.

作者： Zhi-Dong,Zhang ^[1] ; Hong-Xu,Li ^[2] ; Hu,Gan ^[3] ; Zhen,Tang ^[3] ; Yu-Yao,Guo ^[2] ; Shu-Qi,Yao ^[3] ; Tianzi,Liuyu ^[4] ; Bo,Zhong ^[5] ; Dandan,Lin ^[6]

作者单位： Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Department of Pulmonary and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.;Cancer Center, Renmin Hospital of Wuhan University, Wuhan, 430061, China. ^[1] Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Department of Pulmonary and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430071, China. ^[2] Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Department of Pulmonary and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.;Department of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China. ^[3] Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. ^[4] Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Department of Pulmonary and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.;Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.;Department of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China.;Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, 430071, China. ^[5] Cancer Center, Renmin Hospital of Wuhan University, Wuhan, 430061, China. ^[6]

关键词 RAB proteins RNF115 Toll-like receptors intracellular trafficking signaling transduction ubiquitination

主题词内质网(Endoplasmic Reticulum);高尔基体(Golgi Apparatus);免疫(Immunity);Toll样受体(Toll-Like Receptors);泛素化(Ubiquitination)

DOI 10.1002/advs.202105391

PMID 35343654

发布时间 2024-08-29

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2022年9卷16期

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RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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