HSP90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma.

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第一作者： Jo,Sasame

第一单位： Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.;Neurosurgical-Oncology Laboratory, Yokohama City University, Yokohama, Japan.

作者： Jo,Sasame ^[1] ; Naoki,Ikegaya ^[2] ; Masahito,Kawazu ^[3] ; Manabu,Natsumeda ^[4] ; Takahiro,Hayashi ^[1] ; Masataka,Isoda ^[1] ; Kaishi,Satomi ^[5] ; Arata,Tomiyama ^[6] ; Akito,Oshima ^[1] ; Hirokuni,Honma ^[1] ; Yohei,Miyake ^[1] ; Katsuhiro,Takabayashi ^[1] ; Taishi,Nakamura ^[1] ; Toshihide,Ueno ^[7] ; Yuko,Matsushita ^[6] ; Hiromichi,Iwashita ^[8] ; Yu,Kanemaru ^[4] ; Hidetoshi,Murata ^[2] ; Akihide,Ryo ^[9] ; Keita,Terashima ^[10] ; Shoji,Yamanaka ^[8] ; Yukihiko,Fujii ^[4] ; Hiroyuki,Mano ^[7] ; Takashi,Komori ^[11] ; Koichi,Ichimura ^[6] ; Daniel P,Cahill ^[12] ; Hiroaki,Wakimoto ^[12] ; Tetsuya,Yamamoto ^[2] ; Kensuke,Tateishi ^[1]

作者单位： Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.;Neurosurgical-Oncology Laboratory, Yokohama City University, Yokohama, Japan. ^[1] Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan. ^[2] Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.;Division of Cell Therapy, Chiba Cancer Center, Chiba, Japan. ^[3] Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan. ^[4] Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan. ^[5] Deparment of Brain Disease Translational Research, Juntendo University Faculty of Medicine, Tokyo, Japan. ^[6] Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan. ^[7] Department of Pathology, Yokohama City University Hospital, Yokohama, Japan. ^[8] Department of Microbiology, Graduate School of Medicine, Yokohama City University Hospital, Yokohama, Japan. ^[9] Division of Neuro-Oncology, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan. ^[10] Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan. ^[11] Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts.;Translational-Neurooncology Laboratory, Brain Tumor Research Center, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts. ^[12]