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Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.

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第一作者: Pieter Jelle,Visser
第一单位: Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, PO Box 7057 1007, MB, Amsterdam, The Netherlands. pj.visser@amsterdamumc.nl.;Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, PO Box 616, 6200, MD, Maastricht, The Netherlands. pj.visser@amsterdamumc.nl.;Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden. pj.visser@amsterdamumc.nl.
作者单位: Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, PO Box 7057 1007, MB, Amsterdam, The Netherlands. pj.visser@amsterdamumc.nl.;Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, PO Box 616, 6200, MD, Maastricht, The Netherlands. pj.visser@amsterdamumc.nl.;Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden. pj.visser@amsterdamumc.nl. [1] Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, PO Box 7057 1007, MB, Amsterdam, The Netherlands. [2] Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.;Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden. [3] Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands. [4] Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, PO Box 7057 1007, MB, Amsterdam, The Netherlands.;Section Genomics of Neurodegenerative Diseases and Aging, Department of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. [5] 1St Department of Neurology, AHEPA University Hospital, Thessaloniki, Makedonia, Greece. [6] Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, PO Box 616, 6200, MD, Maastricht, The Netherlands. [7] Old Age Psychiatry, University Hospital Lausanne, Lausanne, Switzerland.;Department of Geriatric Psychiatry, University Hospital of Psychiatry and University of Zürich, Zürich, Switzerland. [8] Fundación CITA-Alzhéimer Fundazioa, San Sebastian, Spain. [9] Neurology Service, University Hospitals Leuven, Leuven, Belgium.;Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium. [10] IIB-Sant Pau, Hospital de La Santa Creu I Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain. [11] Barcelonaβeta Brain Research Center (BBRC), Barcelona, Spain.;Alzheimer's Disease Unit and Other Cognitive Disorders Unit, Hospital Clinic de Barcelona, Barcelona, Spain. [12] Reference Center for Biological Markers of Dementia (BIODEM), Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.;Department of Neurology, UZ Brussel and Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium. [13] Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.;Department of Psychiatry at School of Medical Sciences, Örebro University, Örebro, Sweden. [14] Department of Geriatric Psychiatry, Zentralinstitut Für Seelische Gesundheit, University of Heidelberg, Mannheim, Germany. [15] Complex Genetics Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.;Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. [16] Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany. [17] Jansen UK, High Wycombe, UK. [18] Reference Center for Biological Markers of Dementia (BIODEM), Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.;AC Immune SA, Lausanne, Switzerland. [19] Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. [20] Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam University Medical Centers (AUMC), Amsterdam Neuroscience, Netherlands. [21] Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany.;Center for Lifespan Changes in Brain and Cognition, Dept. of Psychology, University of Oslo, Oslo, Norway. [22] Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.;Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.;Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.;Dementia Research Institute at UCL, London, UK. [23]
DOI 10.1186/s13024-022-00521-3
PMID 35346299
发布时间 2022-11-03
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