换一批Novel naltrexone hydrochloride nanovaccine based on chitosan nanoparticles promotes induction of Th1 and Th17 immune responses resulting in protection against Toxoplasma gondii tachyzoites in a mouse model.
第一作者：
Zohreh,Khorshidvand
第一单位：
Department of Medical Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
作者：
医学主题词
佐剂, 免疫(Adjuvants, Immunologic);动物(Animals);抗原, 原虫(Antigens, Protozoan);壳聚糖(Chitosan);疾病模型, 动物(Disease Models, Animal);免疫, 体液(Immunity, Humoral);白细胞介素17(Interleukin-17);白细胞介素4(Interleukin-4);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);纳曲酮(Naltrexone);纳米粒子(Nanoparticles);原虫蛋白质类(Protozoan Proteins);原虫疫苗(Protozoan Vaccines);重组蛋白质类(Recombinant Proteins);Th1细胞(Th1 Cells);Th17细胞(Th17 Cells);弓形虫属(Toxoplasma)
DOI
10.1016/j.ijbiomac.2022.03.146
PMID
35346684
发布时间
2022-05-31
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