首页> Clinical chemistry> ALK-Fusion Transcripts Can Be Detected in Extracellular Vesicles (EVs) from Nonsmall Cell Lung Cancer Cell Lines and Patient Plasma: Toward EV-Based Noninvasive Testing.

ALK-Fusion Transcripts Can Be Detected in Extracellular Vesicles (EVs) from Nonsmall Cell Lung Cancer Cell Lines and Patient Plasma: Toward EV-Based Noninvasive Testing.

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第一作者： Estela,Sánchez-Herrero

第一单位： Liquid Biopsy Laboratory, Medical Oncology Department, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain.;I+D Department, Atrys Health, Barcelona, Spain.

作者： Estela,Sánchez-Herrero ^[1] ; Carmen,Campos-Silva ^[2] ; Yaiza,Cáceres-Martell ^[2] ; Lucía,Robado de Lope ^[3] ; Sandra,Sanz-Moreno ^[3] ; Roberto,Serna-Blasco ^[3] ; Alejandro,Rodríguez-Festa ^[3] ; Dunixe,Ares Trotta ^[3] ; Paloma,Martín-Acosta ^[4] ; Cristina,Patiño ^[5] ; María José,Coronado ^[6] ; Alexandra,Beneitez ^[7] ; Ricardo,Jara ^[7] ; Nerea,Lago-Baameiro ^[8] ; Tamara,Camino ^[8] ; Alberto,Cruz-Bermúdez ^[3] ; María,Pardo ^[8] ; Víctor,González-Rumayor ^[9] ; Mar,Valés-Gómez ^[2] ; Mariano,Provencio ^[10] ; Atocha,Romero ^[10]

作者单位： Liquid Biopsy Laboratory, Medical Oncology Department, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain.;I+D Department, Atrys Health, Barcelona, Spain. ^[1] Department of Immunology and Oncology, Spanish National Centre for Biotechnology, CNB-CSIC, Madrid, Spain. ^[2] Liquid Biopsy Laboratory, Medical Oncology Department, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain. ^[3] Pathology Department, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain. ^[4] Electron Microscopy Unit Centro Nacional de Biotecnología, CSIC, Madrid, Spain. ^[5] Confocal Microscopy Core Facility, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain. ^[6] Immunostep, S.L., Salamanca, Spain. ^[7] Grupo Obesidómica, Área de Endocrinología, Instituto de Investigación Sanitaria de Santiago (IDIS), Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain. ^[8] I+D Department, Atrys Health, Barcelona, Spain. ^[9] Liquid Biopsy Laboratory, Medical Oncology Department, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain.;Medical Oncology Department, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Spain. ^[10]

关键词 ALK-TKI EML4-ALK NSCLC extracellular vesicles liquid biopsy

医学主题词癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系(Cell Line);人类(Humans);肺肿瘤(Lung Neoplasms);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);RNA(RNA);受体蛋白质酪氨酸激酶类(Receptor Protein-Tyrosine Kinases)

DOI 10.1093/clinchem/hvac021

PMID 35348673

发布时间 2022-07-12

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