换一批IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function.
第一作者：
Livia,Casciola-Rosen
第一单位：
Department of Medicine, Division of Rheumatology.
作者：
Livia,Casciola-Rosen [1]
;
David R,Thiemann [2]
;
Felipe,Andrade [1]
;
Maria I,Trejo-Zambrano [1]
;
Elissa K,Leonard [3]
;
Jamie B,Spangler [4]
;
Nicole E,Skinner [5]
;
Justin,Bailey [5]
;
Srinivasan,Yegnasubramanian [6]
;
Rulin,Wang [6]
;
Ajay M,Vaghasia [6]
;
Anuj,Gupta [6]
;
Andrea L,Cox [5]
;
Stuart C,Ray [5]
;
Raleigh M,Linville [7]
;
Zhaobin,Guo [8]
;
Peter C,Searson [9]
;
Carolyn E,Machamer [10]
;
Stephen,Desiderio [11]
;
Lauren M,Sauer [12]
;
Oliver,Laeyendecker [13]
;
Brian T,Garibaldi [14]
;
Li,Gao [15]
;
Mahendra,Damarla [16]
;
Paul M,Hassoun [16]
;
Jody E,Hooper [17]
;
Christopher A,Mecoli [1]
;
Lisa,Christopher-Stine [1]
;
Laura,Gutierrez-Alamillo [1]
;
Qingyuan,Yang [1]
;
David,Hines [1]
;
William A,Clarke [17]
;
Richard E,Rothman [18]
;
Andrew,Pekosz [19]
;
Katherine Zj,Fenstermacher [20]
;
Zitong,Wang [21]
;
Scott L,Zeger [22]
;
Antony,Rosen [23]
作者单位：
Department of Medicine, Division of Rheumatology.
[1]
Department of Medicine, Division of Cardiology; and.
[2]
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[3]
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.;Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.;Translational Tissue Engineering Center.
[4]
Department of Medicine, Division of Infectious Diseases; and.
[5]
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[6]
Institute for NanoBioTechnology and.;Department of Materials Science and Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
[7]
Institute for NanoBioTechnology and.
[8]
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.;Institute for NanoBioTechnology and.;Department of Materials Science and Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
[9]
Department of Cell Biology and.
[10]
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[11]
Adult Emergency Department, Johns Hopkins Hospital, Baltimore, Maryland, USA.;Johns Hopkins Biocontainment Unit, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[12]
Department of Medicine, Division of Infectious Diseases; and.;Division of Intramural Medicine, National Institute of Allergy and Infectious Diseases, NIH, Baltimore, Maryland, USA.
[13]
Johns Hopkins Biocontainment Unit, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.;Department of Medicine, Division of Pulmonary and Critical Care Medicine.
[14]
Department of Medicine, Division of Allergy and Clinical Immunology; and.
[15]
Department of Medicine, Division of Pulmonary and Critical Care Medicine.
[16]
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[17]
Adult Emergency Department, Johns Hopkins Hospital, Baltimore, Maryland, USA.
[18]
Department of Environmental Health and Engineering.;Department of Molecular Microbiology and Immunology, and.
[19]
Department of Environmental Health and Engineering.
[20]
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
[21]
Department of Medicine, Division of Rheumatology.;Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
[22]
Department of Medicine, Division of Rheumatology.;Department of Cell Biology and.;Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[23]
DOI
10.1172/jci.insight.158362
PMID
35349483
发布时间
2025-07-19
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JCI insight
2022年7卷9期
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