换一批
第一作者：
Marciela M,DeGrace
第一单位：
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Division of Microbiology and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.
作者：
Marciela M,DeGrace [1]
;
Elodie,Ghedin [2]
;
Matthew B,Frieman [3]
;
Florian,Krammer [4]
;
Alba,Grifoni [5]
;
Arghavan,Alisoltani [6]
;
Galit,Alter [7]
;
Rama R,Amara [8]
;
Ralph S,Baric [9]
;
Dan H,Barouch [10]
;
Jesse D,Bloom [11]
;
Louis-Marie,Bloyet [12]
;
Gaston,Bonenfant [13]
;
Adrianus C M,Boon [14]
;
Eli A,Boritz [15]
;
Debbie L,Bratt [16]
;
Traci L,Bricker [14]
;
Liliana,Brown [1]
;
William J,Buchser [17]
;
Juan Manuel,Carreño [18]
;
Liel,Cohen-Lavi [19]
;
Tamarand L,Darling [14]
;
Meredith E,Davis-Gardner [20]
;
Bethany L,Dearlove [21]
;
Han,Di [13]
;
Meike,Dittmann [22]
;
Nicole A,Doria-Rose [23]
;
Daniel C,Douek [23]
;
Christian,Drosten [24]
;
Venkata-Viswanadh,Edara [20]
;
Ali,Ellebedy [25]
;
Thomas P,Fabrizio [26]
;
Guido,Ferrari [27]
;
Will M,Fischer [28]
;
William C,Florence [1]
;
Ron A M,Fouchier [29]
;
John,Franks [26]
;
Adolfo,García-Sastre [30]
;
Adam,Godzik [6]
;
Ana Silvia,Gonzalez-Reiche [31]
;
Aubree,Gordon [32]
;
Bart L,Haagmans [29]
;
Peter J,Halfmann [33]
;
David D,Ho [34]
;
Michael R,Holbrook [35]
;
Yaoxing,Huang [34]
;
Sarah L,James [36]
;
Lukasz,Jaroszewski [6]
;
Trushar,Jeevan [26]
;
Robert M,Johnson [3]
;
Terry C,Jones [37]
;
Astha,Joshi [14]
;
Yoshihiro,Kawaoka [38]
;
Lisa,Kercher [26]
;
Marion P G,Koopmans [29]
;
Bette,Korber [28]
;
Eilay,Koren [39]
;
Richard A,Koup [23]
;
Eric B,LeGresley [36]
;
Jacob E,Lemieux [40]
;
Mariel J,Liebeskind [17]
;
Zhuoming,Liu [12]
;
Brandi,Livingston [26]
;
James P,Logue [3]
;
Yang,Luo [34]
;
Adrian B,McDermott [23]
;
Margaret J,McElrath [41]
;
Victoria A,Meliopoulos [26]
;
Vineet D,Menachery [42]
;
David C,Montefiori [43]
;
Barbara,Mühlemann [37]
;
Vincent J,Munster [44]
;
Jenny E,Munt [45]
;
Manoj S,Nair [34]
;
Antonia,Netzl [36]
;
Anna M,Niewiadomska [46]
;
Sijy,O'Dell [23]
;
Andrew,Pekosz [47]
;
Stanley,Perlman [48]
;
Marjorie C,Pontelli [12]
;
Barry,Rockx [29]
;
Morgane,Rolland [21]
;
Paul W,Rothlauf [12]
;
Sinai,Sacharen [39]
;
Richard H,Scheuermann [46]
;
Stephen D,Schmidt [23]
;
Michael,Schotsaert [49]
;
Stacey,Schultz-Cherry [26]
;
Robert A,Seder [23]
;
Mayya,Sedova [6]
;
Alessandro,Sette [50]
;
Reed S,Shabman [1]
;
Xiaoying,Shen [27]
;
Pei-Yong,Shi [51]
;
Maulik,Shukla [52]
;
Viviana,Simon [53]
;
Spencer,Stumpf [12]
;
Nancy J,Sullivan [23]
;
Larissa B,Thackray [14]
;
James,Theiler [28]
;
Paul G,Thomas [54]
;
Sanja,Trifkovic [26]
;
Sina,Türeli [36]
;
Samuel A,Turner [36]
;
Maria A,Vakaki [17]
;
Harm,van Bakel [31]
;
Laura A,VanBlargan [14]
;
Leah R,Vincent [1]
;
Zachary S,Wallace [55]
;
Li,Wang [13]
;
Maple,Wang [34]
;
Pengfei,Wang [34]
;
Wei,Wang [56]
;
Scott C,Weaver [42]
;
Richard J,Webby [26]
;
Carol D,Weiss [56]
;
David E,Wentworth [13]
;
Stuart M,Weston [3]
;
Sean P J,Whelan [12]
;
Bradley M,Whitener [14]
;
Samuel H,Wilks [36]
;
Xuping,Xie [51]
;
Baoling,Ying [14]
;
Hyejin,Yoon [28]
;
Bin,Zhou [13]
;
Tomer,Hertz [57]
;
Derek J,Smith [58]
;
Michael S,Diamond [59]
;
Diane J,Post [60]
;
Mehul S,Suthar [61]
作者单位：
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Division of Microbiology and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.
[1]
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Systems Genomics Section, Laboratory of Parasitic Diseases, National Institutes of Health, Rockville, MD, USA.
[2]
Center for Pathogen Research, Department of Microbiology and Immunology, The University of Maryland School of Medicine, Baltimore, MD, USA.
[3]
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. florian.krammer@mssm.edu.;Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. florian.krammer@mssm.edu.
[4]
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA.
[5]
University of California Riverside School of Medicine, Riverside, CA, USA.
[6]
Ragon Institute of MGH, MIT, and Harvard, Boston, MA, USA.
[7]
Department of Microbiology and Immunology, Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA, USA.
[8]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Department of Microbiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
[9]
Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.
[10]
Fred Hutch Cancer Center, Howard Hughes Medical Institute, Seattle, WA, USA.
[11]
Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
[12]
CDC COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, GA, USA.
[13]
Department of Medicine, Washington University in St Louis, St Louis, MO, USA.
[14]
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Division of Microbiology and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Vaccine Research Center, Bethesda, MD, USA.
[15]
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Division of Microbiology and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;CAMRIS, Contractor for NIAID, Bethesda, MD, USA.
[16]
High Throughput Screening Center, Washington University School of Medicine, St Louis, MO, USA.
[17]
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[18]
National Institute for Biotechnology in the Negev, Department of Industrial Engineering and Management, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
[19]
Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
[20]
US Military HIV Research Program, Henry M. Jackson Foundation for the Advancement of Military Medicine, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
[21]
Microbiology Department, New York University Grossman School of Medicine, New York, NY, USA.
[22]
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.;Vaccine Research Center, Bethesda, MD, USA.
[23]
Institute of Virology, Charité-Universitätsmedizin and German Center for Infection Research (DZIF), Berlin, Germany.
[24]
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
[25]
Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN, USA.
[26]
Department of Surgery, Duke University Medical Center, Durham, NC, USA.
[27]
Los Alamos National Laboratory, New Mexico Consortium, Los Alamos, NM, USA.
[28]
Department Viroscience, Erasmus MC, Rotterdam, The Netherlands.
[29]
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[30]
Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[31]
Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.
[32]
Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.
[33]
Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
[34]
National Institute of Allergy and Infectious Diseases Integrated Research Facility, Frederick, MD, USA.
[35]
Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, UK.
[36]
Institute of Virology, Charité-Universitätsmedizin and German Center for Infection Research (DZIF), Berlin, Germany.;Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, UK.
[37]
Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.;Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.;Disease Control and Prevention Center, National Center for Global Health and Medicine Hospital, Tokyo, Japan.
[38]
National Institute for Biotechnology in the Negev, Department of Industrial Engineering and Management, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.;The Shraga Segal Department of Microbiology and Immunology, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
[39]
Broad Institute of MIT and Harvard, Boston, MA, USA.
[40]
Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
[41]
Department of Microbiology and Immunology, Institute for Human Infection and Immunity, World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.
[42]
Duke University Medical Center, Durham, NC, USA.
[43]
Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
[44]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
[45]
Department of Informatics, J. Craig Venter Institute, La Jolla, CA, USA.
[46]
Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
[47]
Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
[48]
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[49]
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA.;Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA, USA.
[50]
Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, TX, USA.
[51]
University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.;Data Science and Learning Division, Argonne National Laboratory, Argonne, IL, USA.
[52]
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[53]
Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
[54]
Department of Informatics, J. Craig Venter Institute, La Jolla, CA, USA.;Department of Computer Science and Engineering, University of California, San Diego, CA, USA.
[55]
Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA.
[56]
Department of Microbiology, Immunology and Genetics Faculty of Health Sciences Ben-Gurion University of the Negev, Be'er Sheva, Israel. thertz@bgu.ac.il.
[57]
Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, UK. djs200@cam.ac.uk.
[58]
Department of Medicine, Washington University in St Louis, St Louis, MO, USA. mdiamond@wustl.edu.;Department of Pathology & Immunology, Washington University School of Medicine, St Louis, MO, USA. mdiamond@wustl.edu.;Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA. mdiamond@wustl.edu.;The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, MO, USA. mdiamond@wustl.edu.
[59]
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA. postd@niaid.nih.gov.;Division of Microbiology and Infectious Diseases, National Institutes of Health, Rockville, MD, USA. postd@niaid.nih.gov.
[60]
Center for Childhood Infections and Vaccines of Children's Healthcare of Atlanta, Department of Pediatrics, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA. mehul.s.suthar@emory.edu.
[61]
医学主题词
动物(Animals);生物进化(Biological Evolution);人类(Humans);国立变态反应与感染性疾病研究所(美国)(National Institute of Allergy and Infectious Diseases (U.S.));疾病大流行(Pandemics);美国(United States);毒力(Virulence)
DOI
10.1038/s41586-022-04690-5
PMID
35361968
发布时间
2026-05-28
基金项目
U19 AI135995/AI/NIAID NIH HHS/United States
R01 AI157155/AI/NIAID NIH HHS/United States
HHMI/Howard Hughes Medical Institute/United States
R01 AI153602/AI/NIAID NIH HHS/United States
MR/V007025/1/MRC_/Medical Research Council/United Kingdom
UM1 AI068618/AI/NIAID NIH HHS/United States
P01 AI060699/AI/NIAID NIH HHS/United States
R24 AI120942/AI/NIAID NIH HHS/United States
S10 OD030463/OD/NIH HHS/United States
75N93021C00014/AI/NIAID NIH HHS/United States
75N93019C00051/AI/NIAID NIH HHS/United States
75N93019D00025/AI/NIAID NIH HHS/United States
R01 AI154470/AI/NIAID NIH HHS/United States
75N91019D00024/CA/NCI NIH HHS/United States
U01 AI150747/AI/NIAID NIH HHS/United States
HHSN272201400008C/AI/NIAID NIH HHS/United States
T32 AI007524/AI/NIAID NIH HHS/United States
P51 OD011132/OD/NIH HHS/United States
R01 AI134907/AI/NIAID NIH HHS/United States
75N93021C00017/AI/NIAID NIH HHS/United States
R01 AI120997/AI/NIAID NIH HHS/United States
U01 AI141990/AI/NIAID NIH HHS/United States
ZIA AI005156/ImNIH/Intramural NIH HHS/United States
U19 AI057266/AI/NIAID NIH HHS/United States
U01 CA260476/CA/NCI NIH HHS/United States
U01 AI151810/AI/NIAID NIH HHS/United States
R37 AI080289/AI/NIAID NIH HHS/United States
75N93019C00076/AI/NIAID NIH HHS/United States
HHSN272201400006C/AI/NIAID NIH HHS/United States
R01 AI042790/AI/NIAID NIH HHS/United States
75N93021C00016/AI/NIAID NIH HHS/United States
S10 OD026880/OD/NIH HHS/United States
R01 AI146785/AI/NIAID NIH HHS/United States
U01 AI144616/AI/NIAID NIH HHS/United States
P01 AI158571/AI/NIAID NIH HHS/United States
R01 AI129269/AI/NIAID NIH HHS/United States
75N93019C00050/AI/NIAID NIH HHS/United States
HHSN272201800013C/AI/NIAID NIH HHS/United States
R01 AI136514/AI/NIAID NIH HHS/United States
R01 AI141707/AI/NIAID NIH HHS/United States
R01 AI148378/AI/NIAID NIH HHS/United States
HHSN272201700060C/AI/NIAID NIH HHS/United States
HHSN272201400007C/AI/NIAID NIH HHS/United States
R01 AI143639/AI/NIAID NIH HHS/United States
75N93019C00052/AI/NIAID NIH HHS/United States
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