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T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma.

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作者单位: University Medical Center Freiburg, Clinic for Internal Medicine II, Germany. [1] University Medical Center Freiburg, Institute for Medical Biometry and Statistics (IMBI), Germany. [2] University of Pennsylvania, Perelman School of Medicine, Institute for Immunology, USA. [3] University Medical Center Freiburg, Institute of Clinical Pathology, Germany. [4] University Medical Center Freiburg, Clinic for General and Visceral Surgery, Germany. [5] Leipzig University Medical Center, Division of Hepatology, Dpt. of Medicine II, Germany. [6] Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Humanitas Cancer Center, Medical Oncology and Hematology Unit, Rozzano (Milan), Italy. [7] Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Pathology Unit IRCCS Humanitas Research Hospital Rozzano, Milan, Italy. [8] Department of Medicine, Division of Medical Oncology, Kansas University Cancer Center, Kansas City, Kansas, USA. [9] Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; Imperial College London, Faculty of Medicine, Department of Surgery & Cancer, UK. [10] Imperial College London, Faculty of Medicine, Department of Surgery & Cancer, UK; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy. [11] University Medical Center Freiburg, Clinic for Internal Medicine II, Germany; University of Freiburg, Signalling Research Centres BIOSS and CIBSS, Germany; German Cancer Consortium (DKTK), Partner Site Freiburg, Germany. Electronic address: bertram.bengsch@uniklinik-freiburg.de. [12]
DOI 10.1016/j.jhep.2022.02.032
PMID 35367533
发布时间 2022-10-04
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