首页> Frontiers in immunology> The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells.

The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells.

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第一作者： Anila,Vadakumchery

第一单位： Institute of Immunology, Ulm University Medical Center, Ulm, Germany.

作者： Anila,Vadakumchery ^[1] ; Hemin,Faraidun ^[2] ; Omar El,Ayoubi ^[1] ; Issame,Outaleb ^[2] ; Vera,Schmid ^[1] ; Hend,Abdelrasoul ^[1] ; Timm,Amendt ^[1] ; Ahmad,Khadour ^[1] ; Corinna,Setz ^[1] ; Katharina,Göhring ^[1] ; Karoline,Lodd ^[1] ; Christoffer,Hitzing ^[3] ; Alabbas,Alkhatib ^[2] ; Mayas,Bilal ^[1] ; Julian,Benckendorff ^[4] ; Abdul Kader,Al Shugri ^[4] ; Cord Herbert,Brakebusch ^[5] ; Niklas,Engels ^[3] ; Moumita,Datta ^[1] ; Elias,Hobeika ^[1] ; Ameera,Alsadeq ^[1] ; Hassan,Jumaa ^[6]

作者单位： Institute of Immunology, Ulm University Medical Center, Ulm, Germany. ^[1] Department of Molecular Immunology, Faculty of Biology, Albert Ludwigs University of Freiburg, Freiburg, Germany. ^[2] Institute of Cellular & Molecular Immunology, University Medical Center Göttingen, Göttingen, Germany. ^[3] Institute of Pathology, Ulm University Medical Center, Ulm, Germany. ^[4] Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark. ^[5] Institute of Immunology, Ulm University Medical Center, Ulm, Germany.;Department of Molecular Immunology, Faculty of Biology, Albert Ludwigs University of Freiburg, Freiburg, Germany. ^[6]

关键词 BCR-ABL CLL PI3K signaling PTEN RHOA SLP65