Effects of oral losartan administration on homeostasis of articular cartilage and bone in a rabbit model.
第一作者:
Zhenhan,Deng
第一单位:
Department of Orthopaedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
作者:
关键词
2D, 2 dimension3D, 3 dimensionAGTR1, angiotensin II receptor type 1AGTR2, angiotensin II receptor type 2ARRIVE, Animal Research: Reporting of In Vivo ExperimentsAT1, angiotensin type 1AngII, angiotensin IIArticular cartilageBV, bone volumeBV/TV, bone volume/total volumeBoneCol1, collagen type ICol3, collagen type 3Ct.Th, cortical thicknessDMM, destabilization of the medial meniscusEDTA, ethylenediaminetetraacetic acid disodium dihydrateH&E, Hematoxylin &eosinHomeostasisLosartanMicro-CT, Micro-computer tomographyMicrofractureOCN, osteocalcinRA, rheumatoid arthritisRAS, rennin-angiotensin systemSMAD7, mothers against decapentaplegic homolog 7Tb.N, trabecular numberTb.Sp, trabecular seperationTb.Th, trabecular thicknesspSMAD2/3, phosphorylated mothers against decapentaplegic homologpTAK1, phosphorylated transforming growth factor β (TGF-β)-activated kinase 1
DOI
10.1016/j.bonr.2022.101526
PMID
35372645
发布时间
2022-04-05
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Bone reports
2022年16卷
101526页
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