Concerted modification of nucleotides at functional centers of the ribosome revealed by single-molecule RNA modification profiling.

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作者： Andrew D,Bailey ^[1] ; Jason,Talkish ^[2] ; Hongxu,Ding ^[3] ; Haller,Igel ^[2] ; Alejandra,Duran ^[4] ; Shreya,Mantripragada ^[5] ; Benedict,Paten ^[1] ; Manuel,Ares ^[2]

作者单位： Department of Biomolecular Engineering and Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, United States. ^[1] RNA Center and Department of Molecular, Cell & Developmental Biology, University of California, Santa Cruz, Santa Cruz, United States. ^[2] Department of Biomolecular Engineering and Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, United States.;Department of Pharmacy Practice & Science, College of Pharmacy, University of Arizona, Tucson, United States. ^[3] Colegio Santa Francisca Romana, Bogotá, Colombia. ^[4] Monta Vista High School, Cupertino, United States. ^[5]

关键词 RNA modification S. cerevisiae cell biology computational biology helicase nanopore ribosome snoRNA snoRNP systems biology

主题词甲基化(Methylation);核苷酸类(Nucleotides);RNA(RNA);RNA前体(RNA Precursors);RNA, 核糖体(RNA, Ribosomal);核糖体(Ribosomes)

DOI 10.7554/eLife.76562

PMID 35384842

发布时间 2024-09-23

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