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首页> Proceedings of the National Academy of Sciences of the United States of America> PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections.

PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections.

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作者： Swati,Shah ^[1] ; Sanhita,Sinharay ^[1] ; Reema,Patel ^[1] ; Jeffrey,Solomon ^[2] ; Ji Hyun,Lee ^[3] ; William,Schreiber-Stainthorp ^[1] ; Falguni,Basuli ^[4] ; Xiang,Zhang ^[4] ; Katie R,Hagen ^[3] ; Rebecca,Reeder ^[3] ; Paul,Wakim ^[5] ; Louis M,Huzella ^[3] ; Dragan,Maric ^[6] ; Reed F,Johnson ^[7] ; Dima A,Hammoud ^[1]

作者单位： Center for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, NIH, Bethesda, MD 20892. ^[1] Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD 21702. ^[2] Integrated Research Facility, National Institute of Allergy and Infectious Diseases, NIH, Frederick, MD 21702. ^[3] Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, NIH, Rockville, MD 20824. ^[4] Biostatistics and Clinical Epidemiology Service, Clinical Center, NIH, Bethesda, MD 20892. ^[5] Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892. ^[6] Emerging Viral Pathogens Section, National Institute of Allergy and Infectious Diseases, NIH, Frederick, MD 21702. ^[7]

关键词 DPA714 Ebola virus PET imaging macaque

主题词动物(Animals);疾病模型, 动物(Disease Models, Animal);出血热, 埃博拉(Hemorrhagic Fever, Ebola);肺(Lung);猕猴(Macaca mulatta);正电子发射断层显像术(Positron-Emission Tomography);吡唑类(Pyrazoles);嘧啶类(Pyrimidines);受体, GABA(Receptors, GABA);脾(Spleen)

DOI 10.1073/pnas.2110846119

PMID 35385353

发布时间 2024-09-23

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Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America

2022年119卷15期

e2110846119页

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Proceedings of the National Academy of Sciences of the United States of America

2022年119卷15期

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