POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function.

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第一作者： Minghui,Yao

第一单位： State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China. Electronic address: mhyao@genetics.ac.cn.

作者： Minghui,Yao ^[1] ; Meizhen,Meng ^[2] ; Xiyu,Yang ^[2] ; Shuo,Wang ^[3] ; Hongsheng,Zhang ^[4] ; Feng,Zhang ^[3] ; Lei,Shi ^[5] ; Yongqing,Zhang ^[3] ; Xiaohui,Zhang ^[6] ; Zhiheng,Xu ^[7]

作者单位： State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China. Electronic address: mhyao@genetics.ac.cn. ^[1] State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China. ^[2] State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China. ^[3] Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China. ^[4] State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. ^[5] State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China. Electronic address: xhzhang@bnu.edu.cn. ^[6] State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China; Parkinson's Disease Center, Beijing Institute for Brain Disorders, Beijing 100101, China. Electronic address: zhxu@genetics.ac.cn. ^[7]

关键词 ASD CP: Neuroscience NMDAR POSH PSD-95 SHANK2/3 autistic-like behaviors learning and memory plasticity spine morphology