Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer.

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作者： Sahar K,Hegazy ^[1] ; Gamal A,El-Azab ^[2] ; Fatma,Zakaria ^[3] ; Mohamed F,Mostafa ^[4] ; Reham A,El-Ghoneimy ^[5]

作者单位： Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, El-Gharbia Government, El-Guiesh Street, Tanta 31527, Egypt. Electronic address: sahr.hegazy@pharm.tanta.edu.eg. ^[1] Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, El-Gharbia Government, El-Guiesh Street, Tanta 31527, Egypt. Electronic address: gelazab@yahoo.com. ^[2] Clinical Oncology Department, Faculty of Medicine, Tanta University, El-Gharbia Government, El-Guiesh Street, Tanta 31527, Egypt. Electronic address: fatmaz_555@yahoo.com. ^[3] Clinical Oncology Department, Faculty of Medicine, Alexandria University, Alexandria Government, Egypt. Electronic address: mfarouk69m@gmail.com. ^[4] Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, El-Gharbia Government, El-Guiesh Street, Tanta 31527, Egypt. Electronic address: reham.elghonemy@pharm.tanta.edu.eg. ^[5]

关键词 Carcinoembryonic antigen FOLFOX4 & bevacizumab Mebendazole Mebendazole, 5-Flourouracil, Leucovorin, Oxaliplatin, Bevacizumab, Carcinoembryonic antigen, Vascular endothelial growth factor.Metastatic colorectal cancer Progression free survival Vascular endothelial growth factor