Glucose and MMP-9 dual-responsive hydrogel with temperature sensitive self-adaptive shape and controlled drug release accelerates diabetic wound healing.

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作者： Wanyi,Zhou ^[1] ; Zhiguang,Duan ^[2] ; Jing,Zhao ^[3] ; Rongzhan,Fu ^[1] ; Chenhui,Zhu ^[2] ; Daidi,Fan ^[3]

作者单位： Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an, 710069, Shaanxi, China. ^[1] Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an, 710069, Shaanxi, China. ^[2] Biotech. & Biomed. Research Institute, Northwest University, Xi'an, 710069, Shaanxi, China. ^[3]

关键词 AGEs, advanced glycation end-products BA, Carboxyphenylboric acid CBP, the CS-BA-PVA hydrogel CS, chitosan Cel, celecoxib Diabetic wound healing Dual-responsive GMs, gelatin microspheres IL-10, interleukin-10 INS, insulin MMP-9, matrix metalloproteinase-9 MMPs, matrix metalloproteinases PVA, polyvinyl alcohol STZ, streptozotocin Shape self-adaptive hydrogels TNF-α, Tumornecrosisfactor-α Temperature-sensitive VEGF, vascularendothelialgrowthfactor

DOI 10.1016/j.bioactmat.2022.01.004

PMID 35386439

发布时间 2022-04-08

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Bioactive materials

2022年17卷

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Glucose and MMP-9 dual-responsive hydrogel with temperature sensitive self-adaptive shape and controlled drug release accelerates diabetic wound healing.

Bioactive materials

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Glucose and MMP-9 dual-responsive hydrogel with temperature sensitive self-adaptive shape and controlled drug release accelerates diabetic wound healing.

Bioactive materials

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Bioactive materials

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