首页> Cancer gene therapy> Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis.

Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis.

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第一作者： Deng-Ke,Li

第一单位： Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.

作者： Deng-Ke,Li ^[1] ; Xing-Rui,Chen ^[1] ; Li-Na,Wang ^[2] ; Jia-Hong,Wang ^[1] ; Ji-Ke,Li ^[1] ; Zi-Ying,Zhou ^[1] ; Xin,Li ^[3] ; Lin-Bo,Cai ^[4] ; Shui-Sheng,Zhong ^[4] ; Jing-Jing,Zhang ^[5] ; Yu-Mei,Zeng ^[6] ; Qian-Bing,Zhang ^[1] ; Xiao-Yan,Fu ^[7] ; Xiao-Ming,Lyu ^[8] ; Min-Ying,Li ^[9] ; Zhong-Xi,Huang ^[10] ; Kai-Tai,Yao ^[11]

作者单位： Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. ^[1] Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.;Guangzhou First People's Hospital, School of Medicine, Southern China University of Technology, Guangzhou, 510180, China. ^[2] Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, 518110, China. ^[3] Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China. ^[4] Department of Radiotherapy, Tumor Hospital of Zhongshan People's Hospital, Zhongshan, 528403, China. ^[5] Department of Pathology, Tumor Hospital of Zhongshan People's Hospital, Zhongshan, 528403, China. ^[6] Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Southern Theater Command, People's Liberation Army of China, Guangzhou, 510010, China. ^[7] Department of laboratory medicine, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510000, China. ^[8] Department of Radiotherapy, Tumor Hospital of Zhongshan People's Hospital, Zhongshan, 528403, China. lmy.69@163.com. ^[9] Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. zxhuang@smu.edu.cn. ^[10] Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. ktyao@smu.edu.cn. ^[11]