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Monogenic and Polygenic Contributions to QTc Prolongation in the Population.

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第一作者: Victor,Nauffal
第一单位: Division of Cardiovascular Medicine (V.N.), Brigham and Women's Hospital, Boston, MA.;Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
作者单位: Division of Cardiovascular Medicine (V.N.), Brigham and Women's Hospital, Boston, MA.;Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA. [1] Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA. [2] Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.;Department of Experimental Cardiology, Amsterdam University Medical Centers, The Netherlands (S.J.J.).;Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.). [3] Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.;Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.). [4] Gene Regulation Observatory (A.W.H.), Broad Institute, Cambridge, MA. [5] Center for Genomic Medicine (C.A.-T., H.L.R.), Massachusetts General Hospital, Boston.;Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.). [6] Department of Translational Data Science and Informatics, Geisinger, Danville, PA (C.M.H., B.K.F.). [7] Cardiovascular Genetics Program (S.L.H., E.K.W.), Massachusetts General Hospital, Boston. [8] Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.). [9] McKusick-Nathans Institute, Department of Genetic Medicine (D.E.A.), Johns Hopkins University School of Medicine, Baltimore, MD. [10] Boston University School of Public Health, MA (E.J.B., K.L.L.).;Boston University School of Medicine, MA (E.J.B.). [11] Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston (E.B., A.C.M.). [12] Department of Medicine, University of Mississippi Medical Center, Jackson (Y.-I.M., A.C.). [13] Cardiovascular Health Research Unit and Department of Epidemiology (S.R.H.). [14] Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA (C.K.). [15] Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-University of California-Los Angeles Medical Center, Torrance (H.J.L., J.I.R.). [16] Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York (R.J.F.L.). [17] Department of Biostatistics (K.M.R.). [18] Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.). [19] Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor (T.W.B.). [20] Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore (B.D.M.). [21] Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Systems and Population Health, University of Washington, Seattle, WA (B.M.P.). [22] Division of Cardiology, Department of Medicine (W.S.P.), Johns Hopkins University School of Medicine, Baltimore, MD. [23] Harvard Medical School (S.R.), Brigham and Women's Hospital, Boston, MA. [24] Center for Public Health Genomics and Department of Public Health Sciences, University of Virginia, Charlottesville (S.S.R.). [25] Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston-Salem, NC (E.Z.S.). [26] Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, Cardiology, University of Washington, Seattle, WA (N.S.). [27] Boston University School of Public Health, MA (E.J.B., K.L.L.). [28] Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.;Cardiac Arrhythmia Service and Cardiovascular Research Center (P.T.E., S.A.L.), Massachusetts General Hospital, Boston.;Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.). [29]
DOI 10.1161/CIRCULATIONAHA.121.057261
PMID 35389749
发布时间 2024-06-07
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