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Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus.

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第一作者： Richard K,Perez

第一单位： School of Medicine, University of California, San Francisco, CA, USA.

作者： Richard K,Perez ^[1] ; M Grace,Gordon ^[2] ; Meena,Subramaniam ^[3] ; Min Cheol,Kim ^[4] ; George C,Hartoularos ^[5] ; Sasha,Targ ^[6] ; Yang,Sun ^[7] ; Anton,Ogorodnikov ^[7] ; Raymund,Bueno ^[7] ; Andrew,Lu ^[8] ; Mike,Thompson ^[9] ; Nadav,Rappoport ^[10] ; Andrew,Dahl ^[11] ; Cristina M,Lanata ^[12] ; Mehrdad,Matloubian ^[12] ; Lenka,Maliskova ^[13] ; Serena S,Kwek ^[14] ; Tony,Li ^[14] ; Michal,Slyper ^[15] ; Julia,Waldman ^[15] ; Danielle,Dionne ^[15] ; Orit,Rozenblatt-Rosen ^[15] ; Lawrence,Fong ^[14] ; Maria,Dall'Era ^[1] ; Brunilda,Balliu ^[16] ; Aviv,Regev ^[17] ; Jinoos,Yazdany ^[18] ; Lindsey A,Criswell ^[19] ; Noah,Zaitlen ^[20] ; Chun Jimmie,Ye ^[21]

作者单位： School of Medicine, University of California, San Francisco, CA, USA. ^[1] Biological and Medical Informatics Graduate Program, University of California, San Francisco, CA, USA.;Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA.;Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA. ^[2] Biological and Medical Informatics Graduate Program, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA. ^[3] School of Medicine, University of California, San Francisco, CA, USA.;Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA.;Medical Scientist Training Program, University of California, San Francisco, CA, USA.;UC Berkeley-UCSF Graduate Program in Bioengineering, San Francisco, CA, USA. ^[4] Biological and Medical Informatics Graduate Program, University of California, San Francisco, CA, USA.;Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA. ^[5] School of Medicine, University of California, San Francisco, CA, USA.;Biological and Medical Informatics Graduate Program, University of California, San Francisco, CA, USA.;Medical Scientist Training Program, University of California, San Francisco, CA, USA. ^[6] Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA. ^[7] UCLA-Caltech Medical Scientist Training Program, Los Angeles, CA, USA. ^[8] Department of Computer Science, University of California, Los Angeles, CA, USA. ^[9] Department of Software and Information Systems Engineering, Ben-Gurion University of the Negev, Be'er Sheva, Israel. ^[10] Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL 60637, USA. ^[11] Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, CA, USA. ^[12] Institute for Human Genetics, University of California, San Francisco, CA, USA.;Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. ^[13] Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, CA, USA. ^[14] Klarman Cell Observatory, Broad Institute, Cambridge, MA, USA. ^[15] Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. ^[16] Klarman Cell Observatory, Broad Institute, Cambridge, MA, USA.;Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.;Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[17] Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA. ^[18] Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA.;Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, CA, USA. ^[19] Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA. ^[20] Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA, USA.;Institute for Human Genetics, University of California, San Francisco, CA, USA.;Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, CA, USA.;Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.;Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.;Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.;Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA. ^[21]