Non-psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors-, endocannabinoids-, and NF-κB-mediated signaling.

导出 OA

翻译打印收藏纠错

作者： Vittoria,Borgonetti ^[1] ; Cristina,Benatti ^[2] ; Paolo,Governa ^[3] ; Giovanni,Isoldi ^[4] ; Federica,Pellati ^[5] ; Silvia,Alboni ^[3] ; Fabio,Tascedda ^[2] ; Monica,Montopoli ^[3] ; Nicoletta,Galeotti ^[2] ; Fabrizio,Manetti ^[3] ; Elisabetta,Miraldi ^[6] ; Marco,Biagi ^[7] ; Giovanna,Rigillo ^[1]

作者单位： Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology, University of Florence, Florence, Italy. ^[1] Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy. ^[2] Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy. ^[3] Department of Biotechnology, Chemistry and Pharmacy (Department of Excellence 2018-2022), University of Siena, Siena, Italy. ^[4] Materia Medica Processing S.r.l., Siena, Italy. ^[5] Consorzio Interuniversitario Biotecnologie, Trieste, Italy. ^[6] Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy. ^[7] Department of Physical Sciences, Earth and Environment, University of Siena, Siena, Italy. ^[8]

关键词 Cannabis sativa L.cannabidiol inflammation microglia phytocomplex β-Caryophyllene