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Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial.

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作者: Mrinal M,Gounder [1] ; Albiruni Abdul,Razak [2] ; Neeta,Somaiah [3] ; Sant,Chawla [4] ; Javier,Martin-Broto [5] ; Giovanni,Grignani [6] ; Scott M,Schuetze [7] ; Bruno,Vincenzi [8] ; Andrew J,Wagner [9] ; Bartosz,Chmielowski [10] ; Robin L,Jones [11] ; Richard F,Riedel [12] ; Silvia,Stacchiotti [13] ; Elizabeth T,Loggers [14] ; Kristen N,Ganjoo [15] ; Axel,Le Cesne [16] ; Antoine,Italiano [17] ; Xavier,Garcia Del Muro [18] ; Melissa,Burgess [19] ; Sophie,Piperno-Neumann [20] ; Christopher,Ryan [21] ; Mary F,Mulcahy [22] ; Charles,Forscher [23] ; Nicolas,Penel [24] ; Scott,Okuno [25] ; Anthony,Elias [26] ; Lee,Hartner [27] ; Tony,Philip [28] ; Thierry,Alcindor [29] ; Bernd,Kasper [30] ; Peter,Reichardt [31] ; Lore,Lapeire [32] ; Jean-Yves,Blay [33] ; Christine,Chevreau [34] ; Claudia Maria,Valverde Morales [35] ; Gary K,Schwartz [36] ; James L,Chen [37] ; Hari,Deshpande [38] ; Elizabeth J,Davis [39] ; Garth,Nicholas [40] ; Stefan,Gröschel [41] ; Helen,Hatcher [42] ; Florence,Duffaud [43] ; Antonio Casado,Herráez [44] ; Roberto Diaz,Beveridge [45] ; Giuseppe,Badalamenti [46] ; Mikael,Eriksson [47] ; Christian,Meyer [48] ; Margaret,von Mehren [49] ; Brian A,Van Tine [50] ; Katharina,Götze [51] ; Filomena,Mazzeo [52] ; Alexander,Yakobson [53] ; Aviad,Zick [54] ; Alexander,Lee [55] ; Anna Estival,Gonzalez [56] ; Andrea,Napolitano [8] ; Mark A,Dickson [1] ; Dayana,Michel [57] ; Changting,Meng [57] ; Lingling,Li [57] ; Jianjun,Liu [57] ; Osnat,Ben-Shahar [57] ; Dane R,Van Domelen [57] ; Christopher J,Walker [57] ; Hua,Chang [57] ; Yosef,Landesman [57] ; Jatin J,Shah [57] ; Sharon,Shacham [57] ; Michael G,Kauffman [57] ; Steven,Attia [58]
作者单位: Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY. [1] Princess Margaret Cancer Center, Toronto, Ontario, Canada. [2] The University of Texas MD Anderson Cancer Center, Houston, TX. [3] Sarcoma Oncology Center, Santa Monica, CA. [4] Fundacion Jimenez Diaz University Hospital, Madrid, Madrid, Spain. [5] Division of Medical Oncology, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Torino, Italy. [6] University of Michigan, Ann Arbor, MI. [7] Policlinico Universitario Campus Bio-Medico, Roma, Italy. [8] Dana-Farber Cancer Institute, Boston, MA. [9] Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, CA. [10] The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, United Kingdom. [11] Duke Cancer Institute, Durham, NC. [12] Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy. [13] Fred Hutchinson Cancer Research Center, Seattle, WA. [14] Stanford Cancer Institute, Stanford, CA. [15] Institut Gustave Roussy, Villejuif, France. [16] Institut Bergonié, Bordeaux, France. [17] Catalan Institute of Oncology, IDIBELL, University of Barcelona, Barcelona, Spain. [18] University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA. [19] Institut Curie, Paris, France. [20] Oregon Health & Science University, Portland, OR. [21] The Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL. [22] Cedars-Sinai Medical Center, West Hollywood, CA. [23] Centre Oscar Lambret and Lille University, Lille, France. [24] Mayo Clinic Rochester, Rochester, MN. [25] University of Colorado-Denver, Aurora, CO. [26] University of Pennsylvania, Philadelphia, PA. [27] Northwell Health Physician Partners, New Hyde Park, NY. [28] McGill University Health Centre, Montreal, Quebec, Canada. [29] Mannheim University Medical Center, Mannheim, Germany. [30] Helios Hospital Berlin-Buch, Berlin, Germany. [31] University Hospital Gent, Gent, Belgium. [32] Centre Leon Berard, Lyon, France. [33] Institut Claudius Regaud-IUCT-O, Toulouse, France. [34] Vall d'Hebron University Hospital, Barcelona, Spain. [35] Columbia University Irving Medical Center, New York, NY. [36] The Ohio State James Cancer Center, Columbus, OH. [37] Yale Cancer Center, New Haven, CT. [38] The Vanderbilt Clinic, Nashville, TN. [39] Ottawa Hospital Cancer Center, Ottawa, Ontario, Canada. [40] National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Heidelberg, Germany. [41] Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom. [42] La Timone University Hospital Center and Aix-Marseille University, Marseille, France. [43] Hospital Universitario Clínico San Carlos, Madrid, Spain. [44] Hospital La Fe Valencia, Valencia, Spain. [45] Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy. [46] Skane University Hospital, Lund, Sweden. [47] Johns Hopkins, Baltimore, MD. [48] Fox Chase Cancer Center, Philadelphia, PA. [49] Washington University School of Medicine, St Louis, MO. [50] Klinik und Poliklinik für Innere Medizin III, Hämatologie und Onkologie Klinikum rechts der Isar der TU Muenchen, Marburg, Germany. [51] UCL Saint-Luc, Brussels, Belgium. [52] Soroka University Medical Center, Be'er Sheva, Israel. [53] Faculty of Medicine, Hebrew University of Jerusalem, Israel; The Oncology Department, Hadassah Medical Center, Jerusalem, Israel. [54] The Christie NHS Foundation, Manchester, United Kingdom. [55] Catalan Institute of Oncology (ICO) Germans Trias I Pujol University Hospital, B-ARGO, Barcelona, Spain. [56] Karyopharm Therapeutics Inc, Newton, MA. [57] Mayo Clinic, Jacksonville, FL. [58]
DOI 10.1200/JCO.21.01829
PMID 35394800
发布时间 2024-01-23
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology

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