首页> Journal of experimental & clinical cancer research : CR> Ninjurin1 drives lung tumor formation and progression by potentiating Wnt/β-Catenin signaling through Frizzled2-LRP6 assembly.

Ninjurin1 drives lung tumor formation and progression by potentiating Wnt/β-Catenin signaling through Frizzled2-LRP6 assembly.

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第一作者： Seung Yeob,Hyun

第一单位： Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea.;College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.

作者： Seung Yeob,Hyun ^[1] ; Hye-Young,Min ^[1] ; Ho Jin,Lee ^[2] ; Jaebeom,Cho ^[1] ; Hye-Jin,Boo ^[1] ; Myungkyung,Noh ^[2] ; Hyun-Ji,Jang ^[2] ; Hyo-Jong,Lee ^[3] ; Choon-Sik,Park ^[4] ; Jong-Sook,Park ^[4] ; Young Kee,Shin ^[5] ; Ho-Young,Lee ^[6]

作者单位： Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea.;College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea. ^[1] Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea. ^[2] School of Pharmacy, Sungkyunkwan University, Suwon-Si, Gyeonggi-do, 16419, Republic of Korea. ^[3] Soonchunhyang University Bucheon Hospital, Bucheon-si, Gyeonggi-do, 14584, Republic of Korea. ^[4] College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.;Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea. ^[5] Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea. hylee135@snu.ac.kr.;College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea. hylee135@snu.ac.kr. ^[6]

关键词 Ninjurin1 Wnt signaling cancer stem cell-like subpopulation non-small cell lung cancer