CDK inhibitor Palbociclib targets STING to alleviate autoinflammation.

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第一作者： Jiani,Gao

第一单位： Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

作者： Jiani,Gao ^[1] ; Mengge,Zheng ^[2] ; Xiangyang,Wu ^[2] ; Hang,Zhang ^[2] ; Hang,Su ^[3] ; Yifang,Dang ^[1] ; Mingtong,Ma ^[2] ; Fei,Wang ^[4] ; Junfang,Xu ^[2] ; Li,Chen ^[2] ; Tianhao,Liu ^[2] ; Jianxia,Chen ^[2] ; Fan,Zhang ^[2] ; Li,Yang ^[2] ; Qinghua,Xu ^[4] ; Xuefei,Hu ^[2] ; Heyong,Wang ^[2] ; Yiyan,Fei ^[2] ; Chang,Chen ^[1] ; Haipeng,Liu ^[5]

作者单位： Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. ^[1] Clinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. ^[2] Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai, China. ^[3] Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. ^[4] Central Laboratory, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. ^[5] Institute of Nuclear Medicine, Tongji University School of Medicine, Shanghai, China. ^[6]

关键词 Palbociclib autoinflammatory diseases colitis cyclin-dependent protein kinases stimulator of interferon genes

主题词动物(Animals);自身免疫疾病(Autoimmune Diseases);膜蛋白质类(Membrane Proteins);小鼠(Mice);肿瘤(Neoplasms);哌嗪类(Piperazines);吡啶类(Pyridines)

DOI 10.15252/embr.202153932

PMID 35403787

发布时间 2023-09-16

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