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Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs.

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第一作者： Payal,Arora

第一单位： Early-Research Oral Care, Colgate-Palmolive Company, Piscataway, NJ 08854, USA.

作者： Payal,Arora ^[1] ; Wen,Li ^[2] ; Xiaobin,Huang ^[2] ; Wenjing,Yu ^[2] ; Ranran,Huang ^[2] ; Qian,Jiang ^[2] ; Chider,Chen ^[3]

作者单位： Early-Research Oral Care, Colgate-Palmolive Company, Piscataway, NJ 08854, USA. ^[1] Department of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[2] Department of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.;Center of Innovation & Precision Dentistry, School of Dental Medicine, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[3]

关键词 Indoleamine 2,3 dioxygenase (IDO)RNA-sequencing (RNA-seq)immunomodulation mesenchymal stem cells (MSCs)metabolic reconfiguration periodontal ligament derived stem cells (PDLSCs)prostaglandin E2 (PGE2)

主题词细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);姜黄素(Curcumin);免疫调节(Immunomodulation);间质干细胞(Mesenchymal Stem Cells);牙周韧带(Periodontal Ligament)

DOI 10.3390/ijms23074038

PMID 35409397

发布时间 2025-07-31

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