Safety, Tolerability, and Pharmacokinetic Evaluation of Single and Multiple Doses of the Dipeptidyl Peptidase 1 Inhibitor Brensocatib in Healthy Japanese and White Adults.

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作者： Helen,Usansky ^[1] ; Esther,Yoon ^[2] ; Ariel,Teper ^[1] ; Jun,Zou ^[1] ; Carlos,Fernandez ^[1]

作者单位： Insmed Incorporated, Bridgewater, New Jersey, USA. ^[1] Adventist Health Glendale, USC Verdugo Hills Hospital, Glendale Memorial Hospital and Health Center, Glendale, California, USA. ^[2]

关键词 bronchiectasis dipeptidyl peptidase 1 food effect neutrophil elastase neutrophil serine protease pharmacokinetics

主题词成年人(Adult);苯恶唑类(Benzoxazoles);二肽基肽酶类和三肽基肽酶类(Dipeptidyl-Peptidases and Tripeptidyl-Peptidases);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);氧氮杂|艹卓|类(Oxazepines)

DOI 10.1002/cpdd.1094

PMID 35411669

发布时间 2022-12-07

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Clinical pharmacology in drug development

2022年11卷7期

832-842页

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Safety, Tolerability, and Pharmacokinetic Evaluation of Single and Multiple Doses of the Dipeptidyl Peptidase 1 Inhibitor Brensocatib in Healthy Japanese and White Adults.

Clinical pharmacology in drug development

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Clinical pharmacology in drug development

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Safety, Tolerability, and Pharmacokinetic Evaluation of Single and Multiple Doses of the Dipeptidyl Peptidase 1 Inhibitor Brensocatib in Healthy Japanese and White Adults.

Clinical pharmacology in drug development

相似文献

Clinical pharmacology in drug development

相关期刊

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