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首页> eLife> Aspirin's effect on kinetic parameters of cells contributes to its role in reducing incidence of advanced colorectal adenomas, shown by a multiscale computational study.

Aspirin's effect on kinetic parameters of cells contributes to its role in reducing incidence of advanced colorectal adenomas, shown by a multiscale computational study.

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作者： Yifan,Wang ^[1] ; C Richard,Boland ^[2] ; Ajay,Goel ^[3] ; Dominik,Wodarz ^[1] ; Natalia L,Komarova ^[4]

作者单位： Department of Mathematics, University of California Irvine, Irvine, United States. ^[1] Department of Medicine, University of California San Diego School of Medicine, San Diego, United States. ^[2] Department of Molecular Diagnostics and Experimental Therapeutics, Beckman Research Institute of City of Hope Comprehensive Cancer Center, Duarte, United States. ^[3] Department of Population Health and Disease Prevention, University of California Irvine, Irvine, United States. ^[4]

关键词 advanced adenoma aspirin cancer biology colon cancer computational biology human mathematical modeling systems biology

主题词腺瘤(Adenoma);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);阿司匹林(Aspirin);结直肠肿瘤(Colorectal Neoplasms);人类(Humans);发病率(Incidence);动力学(Kinetics);肿瘤微环境(Tumor Microenvironment)

DOI 10.7554/eLife.71953

PMID 35416770

发布时间 2022-09-13

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