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Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6.

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作者单位: Arnold School of Public Health, Department of Epidemiology & Biostatistics, University of South Carolina, Columbia, SC, USA. [1] Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden. [2] Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA. [3] GeneWerk GmbH, Im Neuenheimer Feld 582, 6910, Heidelberg, Germany. [4] Center for Primary Health Care Research, Lund University, Malmo, Sweden. [5] Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany. [6] Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00, Prague, Czech Republic. [7] Institute of Biology and Medical Genetics, 1st Medical Faculty, Charles University, Albertov 4, 128 00, Prague, Czech Republic. [8] Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, 30605, Pilsen, Czech Republic. [9] Institute of Human Genetics, University of Bonn, Bonn, Germany. [10] Department of Biomedicine, University of Basel, Basel, Switzerland. [11] Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany. [12] Department of Internal Medicine III, University of Ulm, Ulm, Germany. [13] Department of Hematooncology, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic. [14] Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden. [15] Clinical Pharmacology, Department of Integrative Medical Biology, Umea University, Umea, Sweden. [16] Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. [17] Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden. [18] Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. [19] National Centre of Tumor Diseases, Heidelberg, Germany. [20] Division of Computational Genomics, Mayo Clinic, Rochester, MN, USA. [21] Division of Hematology, Mayo Clinic Rochester Mayo Clinic, Rochester, MN, USA. [22] Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany. [23] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany. [24] Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. vachon.celine@mayo.edu. [25] Biomedical Center, Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, 30605, Pilsen, Czech Republic. [26] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120, Heidelberg, Germany. [27]
DOI 10.1038/s41408-022-00658-w
PMID 35418122
发布时间 2022-12-13
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