Estrogen metabolites increase nociceptor hyperactivity in a mouse model of uterine pain.

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第一作者： Zili,Xie

第一单位： Center for the Study of Itch and Sensory Disorders and.

作者： Zili,Xie ^[1] ; Jing,Feng ^[2] ; Tao,Cai ^[1] ; Ronald,McCarthy ^[2] ; Mark D,Eschbach ^[3] ; Yuhui,Wang ^[1] ; Yonghui,Zhao ^[2] ; Zhihua,Yi ^[4] ; Kaikai,Zang ^[5] ; Yi,Yuan ^[6] ; Xueming,Hu ^[1] ; Fengxian,Li ^[2] ; Qin,Liu ^[7] ; Aditi,Das ^[1] ; Sarah K,England ^[2] ; Hongzhen,Hu ^[1]

作者单位： Center for the Study of Itch and Sensory Disorders and. ^[1] Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, USA. ^[2] Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China. ^[3] The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. ^[4] Center for Reproductive Health Sciences, Department of Obstetrics & Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA. ^[5] Department of Bioengineering, Neuroscience Program, University of Illinois Urbana-Champaign, Urbana, Illinois, USA. ^[6] Department of Anesthesiology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ^[7] Department of Nursing, Medical College of Nanchang University, Nanchang, China. ^[8]

关键词 Ion channels Neuroscience Pain

主题词动物(Animals);疾病模型, 动物(Disease Models, Animal);雌激素类(Estrogens);女(雌)性(Female);人类(Humans);小鼠(Mice);疼痛感受器(Nociceptors);骨盆痛(Pelvic Pain);TRPV阳离子通道(TRPV Cation Channels);瞬时受体电位通道(Transient Receptor Potential Channels)

DOI 10.1172/jci.insight.149107

PMID 35420999

发布时间 2022-07-16

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2022年7卷10期

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Estrogen metabolites increase nociceptor hyperactivity in a mouse model of uterine pain.

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Estrogen metabolites increase nociceptor hyperactivity in a mouse model of uterine pain.

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