换一批
换一批Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma.
作者：
Marta,Alonso-Nocelo [1]
;
Laura,Ruiz-Cañas [1]
;
Patricia,Sancho [2]
;
Kıvanç,Görgülü [3]
;
Sonia,Alcalá [1]
;
Coral,Pedrero [1]
;
Mireia,Vallespinos [1]
;
Juan Carlos,López-Gil [1]
;
Marina,Ochando [1]
;
Elena,García-García [4]
;
Sara Maria,David Trabulo [5]
;
Paola,Martinelli [6]
;
Patricia,Sánchez-Tomero [1]
;
Carmen,Sánchez-Palomo [7]
;
Patricia,Gonzalez-Santamaría [8]
;
Lourdes,Yuste [9]
;
Sonja Maria,Wörmann [10]
;
Derya,Kabacaoğlu [3]
;
Julie,Earl [11]
;
Alberto,Martin [12]
;
Fernando,Salvador [12]
;
Sandra,Valle [1]
;
Laura,Martin-Hijano [1]
;
Alfredo,Carrato [13]
;
Mert,Erkan [14]
;
Laura,García-Bermejo [15]
;
Patrick C,Hermann [16]
;
Hana,Algül [3]
;
Gema,Moreno-Bueno [17]
;
Christopher,Heeschen [18]
;
Francisco,Portillo [19]
;
Amparo,Cano [20]
;
Bruno,Sainz [21]
作者单位：
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.;Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Chronic Diseases and Cancer, Area 3, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
[1]
Translational Research Unit, Hospital Miguel Servet, Instituto de Investigacion Sanitaria Aragon, Zaragoza, Spain.
[2]
Comprehensive Cancer Center München, Klinikum rechts der Isar der Technischen Universität München, München, Germany.
[3]
Departamento de Anatomía Patológica, Hospital Universitario Fundación Alcorcón, Alcorcón, Spain.
[4]
Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
[5]
Institute for Cancer Research, Comprehensive Cancer Center, Medizinische Universitat Wien, Wien, Austria.
[6]
Departamento de Anatomía, Histologia y Neurociencia, Universidad Autónoma de Madrid, Madrid, Spain.
[7]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.;Cancer and Human Molecular Genetics, Instituto de Investigación Sanitaria IdiPAZ, Madrid, Spain.
[8]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.;Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Chronic Diseases and Cancer, Area 3, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.;Cancer and Human Molecular Genetics, Instituto de Investigación Sanitaria IdiPAZ, Madrid, Spain.
[9]
Ahmed Cancer Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
[10]
Molecular Epidemiology and Predictive Tumor Markers Group, Chronic Diseases and Cancer, Area 3, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain, Madrid, Spain.;Gastrointestinal Tumours Research Programme, Biomedical Research Network in Cancer (CIBERONC), Madrid, Spain.
[11]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.
[12]
Molecular Epidemiology and Predictive Tumor Markers Group, Chronic Diseases and Cancer, Area 3, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain, Madrid, Spain.;Gastrointestinal Tumours Research Programme, Biomedical Research Network in Cancer (CIBERONC), Madrid, Spain.;Alcala University, Madrid, Spain.
[13]
University Research Center for Translational Medicine - KUTTAM, Istanbul, Turkey.
[14]
Biomarkers and Therapeutic Targets Group, Area 4, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
[15]
Department of Internal Medicine I, Ulm University, Ulm, Germany.
[16]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.;Cancer and Human Molecular Genetics, Instituto de Investigación Sanitaria IdiPAZ, Madrid, Spain.;Breast Cancer Research Programme, Biomedical Research Network in Cancer (CIBERONC), Madrid, Spain.;Fundación MD Anderson Internacional, Madrid, Spain.
[17]
Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.;Center for Single-Cell Omics and Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
[18]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.;Breast Cancer Research Programme, Biomedical Research Network in Cancer (CIBERONC), Madrid, Spain.
[19]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.;Cancer and Human Molecular Genetics, Instituto de Investigación Sanitaria IdiPAZ, Madrid, Spain.;Breast Cancer Research Programme, Biomedical Research Network in Cancer (CIBERONC), Madrid, Spain.
[20]
Departament of Biochemistry, Universidad Autónoma de Madrid (UAM), Departament of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain bsainz@iib.uam.es.;Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Chronic Diseases and Cancer, Area 3, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.;Gastrointestinal Tumours Research Programme, Biomedical Research Network in Cancer (CIBERONC), Madrid, Spain.
[21]
主题词
人类(Humans);小鼠(Mice);动物(Animals);上皮-间质转化(Epithelial-Mesenchymal Transition);胰腺肿瘤(Pancreatic Neoplasms);癌, 胰腺管(Carcinoma, Pancreatic Ductal);疾病模型, 动物(Disease Models, Animal);巨噬细胞(Macrophages);氨基酸氧化还原酶类(Amino Acid Oxidoreductases)
DOI
10.1136/gutjnl-2021-325564
PMID
35428659
发布时间
2024-09-09
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Gut
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345-359页
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