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Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering.

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第一作者： Aiden C,Beauglehole

第一单位： ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, QLD, Australia.;CSL Innovation, Parkville, Victoria, Australia.

作者： Aiden C,Beauglehole ^[1] ; Dinora,Roche Recinos ^[1] ; Cassandra L,Pegg ^[2] ; Yih Yean,Lee ^[3] ; Victor,Turnbull ^[4] ; Susann,Herrmann ^[4] ; Esteban,Marcellin ^[5] ; Christopher B,Howard ^[5] ; Benjamin L,Schulz ^[2]

作者单位： ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, QLD, Australia.;CSL Innovation, Parkville, Victoria, Australia. ^[1] ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, QLD, Australia.;School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia. ^[2] CSL Innovation, Parkville, Victoria, Australia. ^[3] CSL Innovation, Bio21 Institute of Molecular Science and Biotechnology, Parkville, Victoria, Australia. ^[4] ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, QLD, Australia. ^[5]

关键词 Chinese hamster ovary cell bioprocessing cell engineering factor IX production post-translational modifications recombinant factor IX