首页> Cancer cell international> Exosomal miR-301a-3p from esophageal squamous cell carcinoma cells promotes angiogenesis by inducing M2 polarization of macrophages via the PTEN/PI3K/AKT signaling pathway.

Exosomal miR-301a-3p from esophageal squamous cell carcinoma cells promotes angiogenesis by inducing M2 polarization of macrophages via the PTEN/PI3K/AKT signaling pathway.

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第一作者： Yuwei,Shou

第一单位： Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.;Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China.;Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, 450000, China.

作者： Yuwei,Shou ^[1] ; Xiaoqian,Wang ^[2] ; Chao,Chen ^[3] ; Yinghao,Liang ^[2] ; Chenbo,Yang ^[3] ; Qiankun,Xiao ^[2] ; Hui,Li ^[2] ; Shuaiyuan,Wang ^[2] ; Jiao,Shu ^[4] ; Xiangyu,Tian ^[2] ; Kuisheng,Chen ^[5]

作者单位： Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.;Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China.;Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, 450000, China. ^[1] Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, 450000, China. ^[2] Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China.;Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, 450000, China. ^[3] Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.;Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, 450000, China. ^[4] Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China. chenksh2002@163.com.;Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450000, China. chenksh2002@163.com.;Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, 450000, China. chenksh2002@163.com. ^[5]

关键词 Angiogenesis Esophageal squamous cell carcinoma Exosomes Macrophage polarization PI3K/AKT signaling pathway miR-301a-3p

DOI 10.1186/s12935-022-02570-6

PMID 35436935

发布时间 2022-04-23

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