Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses.

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作者： Thavasyappan,Thambi ^[1] ; JinWoo,Hong ^[2] ; A-Rum,Yoon ^[3] ; Chae-Ok,Yun ^[4]

作者单位： Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsimni-ro Seongdong-gu, Seoul, 04763, Korea. ^[1] GeneMedicine CO., Ltd., 222 Wangsimni-ro Seongdong-gu, Seoul, 04763, Seoul, Korea. ^[2] Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsimni-ro Seongdong-gu, Seoul, 04763, Korea.;Hanyang Institute of Bioscience and Biotechnology (HY-IBB), Hanyang University, Seoul, 04763, Korea. ^[3] Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsimni-ro Seongdong-gu, Seoul, 04763, Korea. chaeok@hanyang.ac.kr.;GeneMedicine CO., Ltd., 222 Wangsimni-ro Seongdong-gu, Seoul, 04763, Seoul, Korea. chaeok@hanyang.ac.kr.;Hanyang Institute of Bioscience and Biotechnology (HY-IBB), Hanyang University, Seoul, 04763, Korea. chaeok@hanyang.ac.kr.;Institute of Nano Science and Technology (INST), Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea. chaeok@hanyang.ac.kr. ^[4]

主题词腺病毒科(Adenoviridae);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);溶瘤病毒疗法(Oncolytic Virotherapy);溶瘤病毒(Oncolytic Viruses);聚合物(Polymers)

DOI 10.1038/s41417-022-00469-y

PMID 35444290

发布时间 2024-09-06

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