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Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells.

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第一作者: Muhammad Saad,Khilji
第一单位: Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.;Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia.;Department of Physiology, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
作者单位: Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.;Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia.;Department of Physiology, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan. [1] Department of Medicine, School of Clinical Sciences, Monash Univesity, Clayton, VIC 3168, Australia. [2] Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713 Groningen, The Netherlands. [3] Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. [4] Laboratory of Translational Nutrition Biology, Department of Health Sciences and Technology, Institute of Food, Nutrition and Health, ETH Zürich, 8603 Zürich, Switzerland. [5] Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia. [6] Department of Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark. [7] Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, 2800 Lyngby, Denmark.;Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, San Martín CP1650, Argentina. [8] Laboratory of Medical Genetics, Department of Surgical Medicine, Collegium Medicum, Jan Kochanowski University, 25-369 Kielce, Poland. [9] Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.;Institute of Health Sciences, Collegium Medicum, Jan Kochanowski University, 25-002 Kielce, Poland. [10]
DOI 10.3390/biomedicines10040814
PMID 35453564
发布时间 2022-07-16
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2022年10卷4期

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