Identification and Validation of miR-222-3p and miR-409-3p as Plasma Biomarkers in Gestational Diabetes Mellitus Sharing Validated Target Genes Involved in Metabolic Homeostasis.

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作者： Tiziana,Filardi ^[1] ; Giuseppina,Catanzaro ^[1] ; Giuseppina Emanuela,Grieco ^[2] ; Elena,Splendiani ^[3] ; Sofia,Trocchianesi ^[4] ; Carmela,Santangelo ^[4] ; Roberto,Brunelli ^[5] ; Elisa,Guarino ^[6] ; Guido,Sebastiani ^[7] ; Francesco,Dotta ^[2] ; Susanna,Morano ^[3] ; Elisabetta,Ferretti ^[2]

作者单位： Department of Experimental Medicine, "Sapienza" University, 00161 Rome, Italy. ^[1] Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy. ^[2] Fondazione Umberto di Mario, Toscana Life Sciences, 53100 Siena, Italy. ^[3] Department of Molecular Medicine, "Sapienza" University, 00161 Rome, Italy. ^[4] Center for Gender-Specific Medicine, Gender Specific Prevention and Health Unit, Istituto Superiore di Sanità, 00161 Rome, Italy. ^[5] Maternal and Child Health and Urological Sciences, "Sapienza" University, 00161 Rome, Italy. ^[6] UOC Diabetologia, Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy. ^[7] Tuscany Centre for Precision Medicine (CReMeP), 53100 Siena, Italy. ^[8]

关键词 GDM GDM pathophysiology extracellular vesicles gestational diabetes mellitus miR-222-3p miR-409-3p miRNA pregnancy complications

主题词糖尿病, 2型(Diabetes Mellitus, Type 2);糖尿病, 妊娠(Diabetes, Gestational);女(雌)性(Female);内环境稳定(Homeostasis);人类(Humans);微RNAs(MicroRNAs);妊娠(Pregnancy)

DOI 10.3390/ijms23084276

PMID 35457094

发布时间 2023-03-08

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