DYSF promotes monocyte activation in atherosclerotic cardiovascular disease as a DNA methylation-driven gene.
第一作者:
Xiaokang,Zhang
第一单位:
Center for Gene Diagnosis and Department of Clinical Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
作者:
关键词
1stExonABRABR activator of RhoGEF and GTPaseASCVDCqDEGDMDMGDMPDNA methyltransferase 1DNMT1DYSFEWASFBGFHGAPDHGSEAHDHDL-CHUVECLDL-CMDRENDPBLPLTPPIRPS27SELLSTAT3TCTGTMX1TOMTSSTmUTRWBCWGCNAWTannealing temperatureatherosclerotic cardiovascular diseasesdiabetes mellitusdifferentially expressed genedifferentially methylated genedifferentially methylated probedysferlinepigenome-wide association studyfamilial hypercholesterolemiafasting blood glucosegene set enrichment analysisglyceraldehyde-3-phosphate dehydrogenasehigh-density lipoprotein cholesterolhigh-fat diethuman umbilical vein endothelial celllow-density lipoprotein cholesterolmethylation dependent restriction enzymemethylation-specific qPCRnormal dietox-LDLoxidized low-density lipoproteinperipheral blood leukocyteplateletprotein-protein interactionqMSPquantification cycleribosomal protein S27selectin Lsignal transducer and activator of transcription 3the first exonthioredoxin related transmembrane protein 1topological overlap matrixtotal cholesteroltranscriptional start sitetriglycerideuntranslated regionweighted correlation network analysiswhite blood cellwild type
主题词
动物(Animals);载脂蛋白E类(Apolipoproteins E);动脉粥样硬化(Atherosclerosis);心血管疾病(Cardiovascular Diseases);DNA甲基化(DNA Methylation);人类(Humans);小鼠(Mice);单核细胞(Monocytes)
DOI
10.1016/j.trsl.2022.04.001
PMID
35460889
发布时间
2022-10-06
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Translational research
19-38页
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