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Improved prediction of radiation pneumonitis by combining biological and radiobiological parameters using a data-driven Bayesian network analysis.

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第一作者： Tonaye,Hinton

第一单位： Department of Radiation Oncology, Medical School, The University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109-2026, USA.

作者： Tonaye,Hinton ^[1] ; David,Karnak ^[1] ; Ming,Tang ^[2] ; Ralph,Jiang ^[3] ; Yi,Luo ^[1] ; Philip,Boonstra ^[3] ; Yilun,Sun ^[2] ; Derek J,Nancarrow ^[4] ; Erin,Sandford ^[5] ; Paramita,Ray ^[1] ; Christopher,Maurino ^[1] ; Martha,Matuszak ^[1] ; Matthew J,Schipper ^[2] ; Michael D,Green ^[1] ; Gregory A,Yanik ^[5] ; Muneesh,Tewari ^[5] ; Issam El,Naqa ^[1] ; Caitlin A,Schonewolf ^[1] ; Randall Ten,Haken ^[1] ; Shruti,Jolly ^[1] ; Theodore S,Lawrence ^[1] ; Dipankar,Ray ^[6]

作者单位： Department of Radiation Oncology, Medical School, The University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109-2026, USA. ^[1] Department of Radiation Oncology, Medical School, The University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109-2026, USA; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA. ^[2] Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA. ^[3] Department of Surgery, Division of Hematology-Oncology, Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor, MI, USA. ^[4] Division of Hematology and Oncology, Department of Internal Medicine, Henry Ford Cancer Institute/Henry Ford Hospital, Detroit, MI, USA. ^[5] Department of Radiation Oncology, Medical School, The University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109-2026, USA. Electronic address: dipray@umich.edu. ^[6]

关键词 Data-driven Bayesian network (DD-BN) analysis Inflammatory cytokines MicroRNA (miRNA)Radiation pneumonitis Tumor necrosis factor alpha (TNFα) signaling, nuclear factor kappa B (NFκB)

DOI 10.1016/j.tranon.2022.101428

PMID 35460942

发布时间 2024-09-23

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